When can odds ratios mislead?
When can odds ratios mislead?
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DOI：
10.1136/bmj.316.7136.989
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发表时间：
1998-03-28
影响因子：
--
通讯作者：
Tavakoli, M
中科院分区：
文献类型：
--
作者：
Davies, HTO;Crombie, IK;Tavakoli, M
优势比是衡量效应大小的常用指标，可在病例对照研究、队列研究或临床试验中报告。越来越多地，它们也被用来报告来自系统审查和荟萃分析的结果。赔率比很难直接理解，通常被解释为相当于相对风险。不幸的是，存在一个公认的问题，即当初始风险(即利息结果的流行率)较高时，赔率比与相对风险并不是很接近。因此，存在这样一种危险，即如果将赔率比解释为相对风险，则它们可能会误导。
Odds ratios are a common measure of the size of an effect and may be reported in case-control studies, cohort studies, or clinical trials. Increasingly, they are also used to report the findings from systematic reviews and meta-analyses. Odds ratios are hard to comprehend directly and are usually interpreted as being equivalent to the relative risk. Unfortunately, there is a recognised problem that odds ratios do not approximate well to the relative risk when the initial risk (that is, the prevalence of the outcome of interest) is high. 1 2 Thus there is a danger that if odds ratios are interpreted as though they were relative risks then they may mislead.