The role of dynamic contrast-enhanced MRI in cancer diagnosis and treatment.
The role of dynamic contrast-enhanced MRI in cancer diagnosis and treatment.
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DOI：
10.4261/1305-3825.dir.2537-08.1
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发表时间：
2010-09
期刊：
影响因子：
--
通讯作者：
Choyke PL
中科院分区：
文献类型：
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作者：
Türkbey B;Thomasson D;Pang Y;Bernardo M;Choyke PL
血管生成是肿瘤生长和转移扩散的病理生理学的关键步骤。最近，动态对比增强磁共振成像（DCE-MRI）已成为一种在初始诊断和抗血管生成治疗随访期间评估血管生成的方法。在这篇综述中，我们讨论了在临床实践中实施 DCE-MRI 的技术方面，重点是采集方法和分析技术。
Angiogenesis is a key step in the pathophysiology of tumor growth and metastatic spread. Recently, dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) has emerged as a method for assessing angiogenesis both during the initial diagnosis and for follow up of anti-angiogenic therapies. In this review, we discuss the technical aspects of implementing DCE-MRI in clinical practice with emphasis on acquisition methods and analytic techniques.