Primary yolk sac tumour of the liver in adulthood
Primary yolk sac tumour of the liver in adulthood
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DOI：
10.1136/jcp.51.12.939
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发表时间：
1998-12-01
影响因子：
3.4
通讯作者：
Moorghen, M
中科院分区：
文献类型：
--
作者：
Wong, NACS;D'Costa, H;Moorghen, M
肝脏原发性卵黄囊肿瘤极为罕见。一名 28 岁女性因肝脏囊性肿块和血清甲胎蛋白浓度显着升高而就诊。她因疑似肝细胞癌而接受了部分肝切除术，但肿瘤的组织学检查显示出卵黄囊肿瘤的典型形态学和免疫组织化学特征。没有证据表明肝外主要来源。对该病例以及之前报道的六例成人肝脏原发性卵黄囊肿瘤病例的回顾，揭示了该肿瘤的几个特征，这些特征可能有助于与肝细胞癌的分化，具有潜在的治疗意义。
Primary yolk sac tumour of the liver is exceedingly rare. A 28 year old woman presented with a cystic liver mass and a markedly raised serum a-fetoprotein concentration. She underwent a partial hepatectomy for a suspected hepatocellular carcinoma but histological examination of the tumour revealed the classical morphological and immunohistochemical features of a yolk sac tumour. There was no evidence of an extrahepatic primary source. Review of this case, together with the six previously reported adult cases of primary yolk sac tumours of the liver, revealed several features of the tumour that may aid differentiation from hepatocellular carcinoma, with potential therapeutic implications.