Adequacy of a single stone risk analysis in the medical evaluation of urolithiasis.
Adequacy of a single stone risk analysis in the medical evaluation of urolithiasis.
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单一结石风险分析在尿石症医学评估中的充分性。
DOI：
10.1097/00005392-200102000-00006
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发表时间：
2001
期刊：
影响因子：
--
通讯作者：
Poindexter,JR
中科院分区：
文献类型：
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作者：
Pak,CY;Peterson,R;Poindexter,JR
目的我们测试了这样的假设，即用于结石风险分析的单个 24 小时尿液样本足以简化尿石症的医学评估。材料和方法我们回顾性分析了 225 名复发性尿石症患者在随机和限制饮食期间获得的 24 小时尿液样本的结石风险概况数据。结果在 2 个随机样本中，我们注意到尿钙、草酸盐、尿酸、柠檬酸盐、pH、总体积、钠、钾、硫酸盐或磷。对于这些危险因素，2 个随机样本中存在高度显着的正相关性 (r ≥0.68，p <0.0003)，并且至少 81% 的患者中每个风险因素的值异常或正常。随机样本2中的尿镁和尿铵含量显着低于随机样本1，前者降低了4%。限制钙、钠和草酸盐饮食后，平均尿钙和钠正负标准差显着下降了 25%，从 251 ± 125 降至 187 ± 98 mg。每天增加 38%，从 183 ± 87 至 113 ± 57 mEq。每天，分别。其他危险因素略有变化或无显着变化。由于钠尿排泄过多而校正随机尿钙，使尿钙达到 210 ± 108 mg。每日一次，与限制饮食的值相似。 结论 重复尿样中尿路结石危险因素的重现性令人满意。单一结石风险分析足以简化尿石症的医学评估。
PurposeWe tested the hypothesis that a single 24-hour urine sample for stone risk analysis would be sufficient for the simplified medical evaluation of urolithiasis.Materials and MethodsWe retrospectively analyzed stone risk profile data on 24-hour urine samples obtained during random and restricted diets in 225 patients with recurrent urolithiasis.ResultsIn 2 random samples we noted no significant difference in urinary calcium, oxalate, uric acid, citrate, pH, total volume, sodium, potassium, sulfate or phosphorus. For these risk factors there was a highly significant positive correlation in the 2 random samples (r ≥0.68, p <0.0003) and the value of each was abnormal or normal in at least 81% of patients. Urinary magnesium and ammonium were significantly lower in random sample 2 than 1, the former by 4%. After calcium, sodium and oxalate dietary restriction mean urinary calcium and sodium plus or minus standard deviation decreased significantly by 25% from 251 ± 125 to 187 ± 98 mg. daily and by 38% from 183 ± 87 to 113 ± 57 mEq. daily, respectively. Other risk factors had a slight or no significant change. Correcting random urinary calcium for the excessive urinary excretion of sodium brought urinary calcium to 210 ± 108 mg. daily, similar to the value on the restricted diet.ConclusionsThe reproducibility of urinary stone risk factors is satisfactory in repeat urine samples. A single stone risk analysis is sufficient for the simplified medical evaluation of urolithiasis.