Probable aerosol transmission of severe fever with thrombocytopenia syndrome virus in southeastern China
Probable aerosol transmission of severe fever with thrombocytopenia syndrome virus in southeastern China
复制标题
中国东南部地区可能存在严重发热伴血小板减少综合征病毒气溶胶传播
DOI：
10.1016/j.cmi.2015.07.024
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发表时间：
2015-12-01
影响因子：
14.2
通讯作者：
Chen, Z.
中科院分区：
文献类型：
--
作者：
Gong, Z.;Gu, S.;Chen, Z.
截至2010年，中国报告了一些聚集性重度发热伴血小板减少综合征病毒（SFTSV）感染。然而，迄今为止，还没有SFTSV气溶胶传播的流行病学证据。在2014年5月发生了13例SFTSV病例集群后进行了流行病学调查。除指示患者病例外，共确定了13例病例，包括11例确诊病例和1例临床诊断病例。索引患者于4月23日发生SFTSV，并于5月1日死亡。继发病例的患者于5月10日至16日发病，5月13日达到高峰。此外，8例继发性病例发生在指示患者的家庭成员中，另外5例发生在指示患者的邻居中。根据流行病学调查，患者1、3、4、5、6、7、9和12通过接触指示患者的血液感染了该疾病。值得注意的是，8号和10号患者没有接触过指示患者血液的历史，但他们在灵堂里呆了几个小时。SFTSV可以通过直接接触和/或气溶胶传播在人与人之间传播，重要的是要考虑气溶胶传播作为一种可能的传播途径。临床微生物学和感染（C）2015作者。由Elsevier Ltd代表欧洲临床微生物学和传染病学会出版。
Some clusters of severe fever with thrombocytopenia syndrome virus (SFTSV) infection were reported in China as of 2010. However, to date, there has been no epidemiologic evidence of aerosol transmission of SFTSV. Epidemiologic investigations were conducted after a cluster of 13 cases of SFTSV in May 2014. A total of 13 cases, including 11 confirmed cases and one clinically diagnosed case, were identified besides the case of the index patient. The index patient experienced onset of SFTSV on 23 April and died on 1 May. The patients with secondary cases had onset from 10 to 16 May, peaking on 13 May. Moreover, eight secondary cases occurred in family members of the index patient, and the other five cases occurred in neighbors of the index patient. According to epidemiologic investigations, patients 1, 3, 4, 5, 6, 7, 9 and 12 contracted the disease through contact with blood of the index patient. Notably, patients 8 and 10 did not have a history of contact with the blood of the index patient, but they stayed in the mourning hall for hours. SFTSV could be transmitted from person to person by direct contact and/or aerosol transmission, and it is important to consider aerosol transmission as a possible transmission route. Clinical Microbiology and Infection (C) 2015 The Authors. Published by Elsevier Ltd on behalf of European Society of Clinical Microbiology and Infectious Diseases.