THE PATTERN ERG IN GLAUCOMA - EFFECT OF PATTERN REVERSAL TIME
THE PATTERN ERG IN GLAUCOMA - EFFECT OF PATTERN REVERSAL TIME
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DOI：
10.1007/bf00917963
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发表时间：
1992-09-01
影响因子：
1.6
通讯作者：
MARRE, E
中科院分区：
文献类型：
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作者：
MIERDEL, P;ZENKER, HJ;MARRE, E
具有斜坡状时间过程的模式反转会引起瞬态模式视网膜电图（PERG），与阶梯状过程（突然模式反转）引起的反应相比，其延迟和减弱。这种延迟取决于反转时间，并且可能代表激活的视网膜结构的时间特征的测量。使用具有可调节反转周期的模式反转刺激器（8 X 14 矩形红色发光二极管矩阵，元件尺寸 2 度 X 1 度，刺激区域 16 度 X 14 度）来记录 20 只患有早期或中度视野损伤的青光眼眼睛的瞬态 PERG（通过计算机视野计测量）。阶梯状反转刺激青光眼组与正常人的q波(PI)振幅差异不显着(P=0.23)。另一方面，使用斜坡样刺激时的 PI 潜伏期或阶跃和斜坡样刺激之间的反应潜伏期转变（模式反转时间，30 ms），两组之间可能存在高度显着的分离（P < 0.0001）。
Pattern reversals with a ramp-like temporal course evoke transient pattern electroretinograms (PERG) that are delayed and attenuated in comparison with responses evoked by a step-like course (abrupt pattern reversals). This delay depends on the reversal time and probably represents a measure for temporal characteristics of the activated retinal structures. A pattern reversal stimulator with adjustable reversal periods (matrix of 8 X 14 rectangular red light emitting diodes, element size 2-degrees X 1-degrees, stimulus area 16-degrees X 14-degrees) was used to record transient PERGs from 20 glaucomatous eyes with early or moderate visual field damages (measured with computer perimetry). The q-wave (PI) amplitude difference between the glaucoma group and normal subjects with step-like reversal stimulation was not significant (P = 0.23). On the other hand, a highly significant separation (P < 0.0001) between both groups was possible using the PI latency at ramp-like stimulation or the response latency shift between step and ramp-like stimulation (Pattern reversal time, 30 ms).