Parasites and pesticides act antagonistically on honey bee health
Parasites and pesticides act antagonistically on honey bee health
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DOI：
10.1111/1365-2664.13811
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发表时间：
2021-01-15
影响因子：
5.7
通讯作者：
Hardy, Nate B.
中科院分区：
文献类型：
--
作者：
Bird, Gwendolyn;Wilson, Alan E.;Hardy, Nate B.
杀虫剂和寄生虫都与西方蜜蜂（Apis mellifera）死亡率增加有关。目前，尚不确定是否一个使另一个更糟;几项研究已经测试了潜在的协同应激效应，但结果喜忧参半。在这里，我们对26项研究的63个实验进行了分层荟萃分析，以更清楚地了解寄生虫和杀虫剂对蜜蜂健康的综合影响。我们发现，寄生虫治疗确实往往比单独治疗更致命，但比预测的加性或倍增效应致命性低得多。换句话说，联合治疗效果不是协同的，而是拮抗的。以前关于杀虫剂和寄生虫对蜜蜂健康的联合作用的许多不确定性可以归因于以前的研究中对应激拮抗作用的偏见;许多研究人员已经排除了先验拮抗作用的可能性。合成和应用。荟萃分析表明，当蜜蜂受到杀虫剂和寄生虫组合的压力时，组合压力效应是拮抗的，即小于其部分的总和。更好地了解这种拮抗作用的机制可能对蜜蜂健康的有效管理至关重要。
Pesticides and parasites have each been linked to increased mortality in western honey bees (Apis mellifera). Currently, it is uncertain if one makes the other worse; several studies have tested for potential synergistic stressor effects, but results have been mixed.Here, we use a hierarchical meta-analysis of 63 experiments from 26 studies to gain a clearer view of the combined effects of parasites and pesticides on honey bee health.We found that combined pesticide-parasite treatments do tend to be deadlier than uncombined treatments but are significantly less deadly than predicted additive or multiplicative effects. In other words, combined treatment effects are not synergistic, but antagonistic.Much of the previous uncertainty about the combined effects of pesticides and parasites on honey bee health can be attributed to a bias in the previous research against stressor antagonism; many researchers have excluded the possibility of antagonism a priori.Synthesis and applications. Meta-analysis shows that when honey bees are stressed by a combination of pesticides and parasites, the combined stress effect is antagonistic, that is, less than the sum of its parts. A better understanding of the mechanisms underlying this antagonism could prove critical for effective management of honey bee health.