Drugs of Abuse and Their Impact on Viral Pathogenesis.
Drugs of Abuse and Their Impact on Viral Pathogenesis.
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DOI：
10.3390/v13122387
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发表时间：
2021-11-29
期刊：
影响因子：
--
通讯作者：
Sherman KE
中科院分区：
文献类型：
--
作者：
Blackard JT;Sherman KE
Commonly misused substances such as alcohol, cocaine, heroin, methamphetamine, and opioids suppress immune responses and may impact viral pathogenesis. In recent years, illicit use of opioids has fueled outbreaks of several viral pathogens, including the human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV). This review focuses on the myriad of mechanisms by which drugs of abuse impact viral replication and disease progression. Virus–drug interactions can accelerate viral disease progression and lead to increased risk of virus transmission.
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