Physical function, grip strength and frailty in people living with HIV in sub-Saharan Africa: systematic review.
Physical function, grip strength and frailty in people living with HIV in sub-Saharan Africa: systematic review.
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DOI：
10.1111/tmi.12852
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发表时间：
2017-05
期刊：
影响因子：
--
通讯作者：
de Rekeneire N
中科院分区：
文献类型：
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作者：
Bernard C;Dabis F;de Rekeneire N
介绍目前生活在撒哈拉以南非洲的艾滋病毒感染者的身体机能、握力和脆弱程度的知识，在那里，这一现象在很大程度上被低估了。对Medline、Scope us和African Index Medicus进行了系统检索。我们回顾了截至2016年11月发表的关于撒哈拉以南非洲艾滋病毒携带者(PLHIV)和18岁的文章。在537篇文章中，有13篇是在6个非洲国家进行的，并纳入了本次审查。五篇文章报告了关于功能限制的信息，一篇报告了关于残疾的信息。这5篇文章中有2篇报道了PLHIV的功能受限(步态速度低)。生活在农村和城市的艾滋病病毒携带者中，残疾分别占27%和3%。报告握力的三项研究中有两项报告称，与未感染的患者相比，PLHIV患者的握力较低(近4公斤)。一项研究报告说，PLHIV比未感染HIV的人更容易虚弱(19.4%比13.3%)，而另一项研究报告没有统计学差异。身体机能下降、握力下降和虚弱现在是生活在南沙国家的艾滋病毒感染者的部分负担，但目前的数据不足以描述这些损害的真正公共卫生层面。需要进一步的研究来描述这一重大的公共卫生挑战。由于这可能在不久的将来对非洲医疗保健系统和人力资源造成重大负担，应该制定一种全面护理方法，为指导方针提供参考。
To present the current knowledge on physical function, grip strength and frailty in HIV-infected patients living in sub-Saharan Africa, where the phenomenon is largely underestimated. A systematic search was conducted on Medline, Scopus and African Index Medicus. We reviewed articles on sub-Saharan African people living with HIV (PLHIV) >18 years old, published until November 2016. Of 537 articles, 13 were conducted in six African countries and included in this review. Five articles reported information on functional limitation and one on disability. Two of these 5 articles reported functional limitation (low gait speed) in PLHIV. Disability was observed in 27% and 3% of PLHIV living in rural and urban places, respectively. Two of three studies reporting grip strength reported lower grip strength (nearly 4 kg) in PLHIV in comparison to uninfected patients. One study reported that PLHIV were more likely to be frail than HIV-uninfected individuals (19.4% vs.13.3%) whereas another reported no statistical difference. Decline in physical function, grip strength and frailty are now part of the burden of PLHIV living in SSA countries but current data are insufficient to characterize the real public health dimension of these impairments. Further studies are needed to depict this major public health challenge. As this is likely to contribute to a significant burden on the African healthcare systems and human resources in the near future, a holistic care approach should be developed to inform guidelines.