Results of a surgical resection of pulmonary metastasis from malignant head and neck tumor
Results of a surgical resection of pulmonary metastasis from malignant head and neck tumor
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DOI：
10.1510/icvts.2009.219766
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发表时间：
2010-05-01
影响因子：
--
通讯作者：
Maehara, Yoshihiko
中科院分区：
文献类型：
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作者：
Haro, Akira;Yano, Tokujiro;Maehara, Yoshihiko
关于头颈部恶性肿瘤肺转移的手术切除的报道很少。在此，我们研究肺转移瘤切除术后的生存率，并讨论预后因素。我们回顾性分析了1981年至2008年在九州大学医院接受恶性头颈部肿瘤肺转移切除术的25例患者。我们用Kaplan-Meier法和log-rank （Mantel-Cox）检验评估5年总生存率，使用Stat View软件程序。转移瘤切除术后的3年或5年总生存率分别为53.3%和50.0%。我们调查了临床病理预后因素，包括性别、年龄、组织学、无病间隔、肺转移瘤的数量或大小以及手术方式。年龄（大于60岁）（P = 0.0189）和口腔或咽部鳞状细胞癌的肺转移（P = 0.0002）被认为是不良预后因素。为了获得长期的生存，积极的手术切除被认为是头颈部恶性肿瘤肺转移的有效和标准的治疗方法。然而，也有必要充分阐明这种肺转移的原发部位和组织学。(c) 2010年由欧洲心胸外科协会出版。版权所有。
There have been only a few reports about a surgical resection of pulmonary metastasis from malignant head and neck tumor. Here we investigate the survival after a pulmonary metastasectomy, and discuss the prognostic factors. We retrospectively reviewed 25 patients who underwent a pulmonary metastasectomy from malignant head and neck tumor at Kyushu University Hospital from 1981 through 2008. We assessed the five year overall survival by the Kaplan-Meier method and the log-rank (Mantel-Cox) test using the Stat View software program. The three- or five-year overall survival after a metastasectomy was 53.3% and 50.0%, respectively. We investigated the clinicopathological prognostic factors including gender, age, histology, disease free interval, number or size of pulmonary metastatic tumors, and the operative procedure. Both age (older than 60 years) (P = 0.0189) and pulmonary metastases from squamous cell carcinomas in either oral cavity or pharyngeal region (P = 0.0002) were identified to be adverse prognostic factors. To obtain a long survival, a positive surgical resection is considered to be an effective and standard treatment for pulmonary metastasis from malignant head and neck tumor. It is also necessary, however, to elucidate fully the primary site and histology of such pulmonary metastasis. (c) 2010 Published by European Association for Cardio-Thoracic Surgery. All rights reserved.