Long-term mortality after gastric bypass surgery
Long-term mortality after gastric bypass surgery
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DOI：
10.1056/nejmoa066603
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发表时间：
2007-08-23
影响因子：
158.5
通讯作者：
Hunt, Steven C.
中科院分区：
文献类型：
--
作者：
Adams, Ted D.;Gress, Richard E.;Hunt, Steven C.
背景：尽管胃绕道手术占美国减肥手术的 80%，但与一般人群中的严重肥胖者相比，接受过该手术的患者的死亡率的长期数据有限。方法：在这项回顾性队列研究中，我们确定了 9949 名接受胃绕道手术的患者和 9628 名申请驾驶执照的严重肥胖者的长期死亡率（从 1984 年到 2002 年）。从这些受试者中，7925 名手术患者和 7925 名严重肥胖对照受试者的年龄、性别和体重指数进行了匹配。我们使用国家死亡指数确定了任何原因和特定原因的死亡率。结果：在平均 7.1 年的随访期间，与对照组相比，手术组全因调整后长期死亡率下降了 40%（每万人每年 37.6 例死亡和 57.1 例死亡，P
Background: Although gastric bypass surgery accounts for 80% of bariatric surgery in the United States, only limited long-term data are available on mortality among patients who have undergone this procedure as compared with severely obese persons from a general population. Methods: In this retrospective cohort study, we determined the long-term mortality (from 1984 to 2002) among 9949 patients who had undergone gastric bypass surgery and 9628 severely obese persons who applied for driver's licenses. From these subjects, 7925 surgical patients and 7925 severely obese control subjects were matched for age, sex, and body-mass index. We determined the rates of death from any cause and from specific causes with the use of the National Death Index. Results: During a mean follow-up of 7.1 years, adjusted long-term mortality from any cause in the surgery group decreased by 40%, as compared with that in the control group (37.6 vs. 57.1 deaths per 10,000 person-years, P