Recent advances in understanding female gametophyte development
Recent advances in understanding female gametophyte development
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DOI：
10.12688/f1000research.14508.1
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发表时间：
2018-06
期刊：
影响因子：
--
通讯作者：
D. Skinner;V. Sundaresan
中科院分区：
文献类型：
--
作者：
D. Skinner;V. Sundaresan
单倍体雌配子体（胚囊）是有花植物的基本生殖单位，通常包括四种特化细胞类型，包括雌配子（卵细胞和中央细胞）。这些细胞的分化依赖于空间信号，这些信号沿着近端-远端轴形成配子体，但是在胚囊中确定细胞身份的分子和遗传机制长期以来一直是个谜。最近确定的细胞命运规范的关键基因及其与激素信号通路的关系，作用于位置的线索，这些过程提供了新的见解。一个分化模型可以设计与卵细胞的命运作为默认状态的雌配子体和其他细胞类型的空间调控因子的作用指定。配子体内的细胞间通讯对于维持细胞身份以及促进雄配子（精细胞）对雌配子的受精也很重要。
The haploid female gametophyte (embryo sac) is an essential reproductive unit of flowering plants, usually comprising four specialized cell types, including the female gametes (egg cell and central cell). The differentiation of these cells relies on spatial signals which pattern the gametophyte along a proximal-distal axis, but the molecular and genetic mechanisms by which cell identities are determined in the embryo sac have long been a mystery. Recent identification of key genes for cell fate specification and their relationship to hormonal signaling pathways that act on positional cues has provided new insights into these processes. A model for differentiation can be devised with egg cell fate as a default state of the female gametophyte and with other cell types specified by the action of spatially regulated factors. Cell-to-cell communication within the gametophyte is also important for maintaining cell identity as well as facilitating fertilization of the female gametes by the male gametes (sperm cells).