Right-hemispheric dominance in self-body recognition is altered in left-handed individuals
Right-hemispheric dominance in self-body recognition is altered in left-handed individuals
复制标题
左利手个体的右半球在自我身体识别中的优势发生了改变
DOI：
10.1016/j.neuroscience.2019.10.056
复制
发表时间：
2020
期刊：
影响因子：
3.3
通讯作者：
Naito E
中科院分区：
文献类型：
--
作者：
Morita T;Asada M;Naito E
在人群水平上，视觉自我面部和本体感觉姿势识别主要激活人类右撇子的右下额顶皮质。在本研究中，由于发现左利手可能会改变右利手所观察到的语言、感觉运动和认知功能的偏侧皮层组织，我们调查了 50 名右利手和 50 名左利手在自我身体识别（自我面部和本体感受）任务中皮质使用右手为主的个体差异。我们还研究了左利手在这种以右手为主的使用中可能存在的任务间差异，以及左撇子可能存在的非典型左右反向偏侧化（语言的右手主导和自我身体识别的左手主导）。我们使用功能性磁共振成像测量大脑活动，同时参与者执行本体感觉姿势识别任务（体验左右手的幻觉运动）、视觉自我面部识别（自我他人区分）任务和语言（动词生成）任务。为了评估半球优势，我们计算了这些任务中下额顶叶活动的个体偏侧化指数。左利手改变了在两项自我身体识别任务中大多数右手参与者观察到的右半球优势。在左撇子组中，在本体感觉识别过程中，右偏化、双边化或左偏化的参与者分布均匀，而在自我面部识别过程中，尽管表现出左偏化的参与者数量有所增加，但仍然观察到右偏化。非典型的左右反向偏侧化仅在左撇子参与者中观察到，但在自我身体识别任务期间。本研究提供了关于受左利手影响的右半球在自我身体识别中的优势的新颖且有价值的知识。我们从惯用手、语言偏侧化和发育方面讨论了人类大脑中自我身体识别的功能偏侧化是如何形成的。
Visual self-face and proprioceptive postural recognition predominantly activate the right inferior frontoparietal cortices in human right-handers at the population level. In the present study, prompted by the finding that left-handedness may alter lateralized cortical organization for language, sensory-motor, and cognitive functions observed in right-handers, we investigated individual variations in right-dominant use of the cortices in 50 right-handers and 50 left-handers during self-body recognition (self-face and proprioceptive) tasks. We also investigated possible between-tasks differences in this right-dominant use, and possible atypical left–right reversed lateralization (right-dominance for language and left-dominance for self-body recognition) in left-handers. We measured brain activity using functional magnetic resonance imaging while participants performed a proprioceptive postural recognition task (experiencing illusory movements of the left and the right hands), a visual self-face recognition (self-other distinction) task, and a language (verb generation) task. To evaluate hemispheric dominance, we computed individual lateralization indices for the inferior frontoparietal activities in these tasks. Left-handedness altered the right-hemispheric dominance that was observed in the majority of right-handed participants in both self-body recognition tasks. In the left-handed group, during proprioceptive recognition, participants with right-lateralization, bilaterality, or left-lateralization were equally distributed, and during self-face recognition, right-lateralization was still observed, though the number of participants who demonstrated left-lateralization increased. Atypical left–right reversed lateralization was only observed in left-handed participants, but during both self-body recognition tasks. The present study provides novel and valuable knowledge about right-hemispheric dominance in self-body recognition affected by left-handedness. We discuss how functional lateralization of self-body recognition is shaped in human brain, in terms of handedness, language lateralization, and development.