Seasonal assembly of skin microbiota driven by neutral and selective processes in the greater horseshoe bat
Seasonal assembly of skin microbiota driven by neutral and selective processes in the greater horseshoe bat
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DOI：
10.1111/mec.17051
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发表时间：
2023-06
影响因子：
4.9
通讯作者：
Aoqiang Li;Zhongle Li;Haixia Leng;Longru Jin;Yanhong Xiao;Keping Sun;Jiang Feng
中科院分区：
文献类型：
--
作者：
Aoqiang Li;Zhongle Li;Haixia Leng;Longru Jin;Yanhong Xiao;Keping Sun;Jiang Feng
皮肤微生物区系在保护蝙蝠宿主免受破坏性假淋巴曲霉真菌的侵袭中起着重要作用，这种真菌已经导致蝙蝠数量急剧下降和灭绝。最近的研究已经对蝙蝠皮肤的细菌群落有了深入的了解，但在真菌入侵的季节性动态背景下，皮肤细菌群落结构的变化以及驱动这种变化的过程在很大程度上仍未被探索。在这项研究中，我们描述了蝙蝠冬眠和活跃季节阶段的皮肤微生物区系，并使用群落生态学的中性模型来确定中性和选择性过程在驱动微生物群落变化中的相对作用。我们的结果显示，冬眠期间的皮肤群落结构发生了显著的季节性变化，微生物区系的多样性也低于活动季节。皮肤微生物区系受环境细菌库的影响。在冬眠和旺季阶段，蝙蝠皮肤微生物区系中超过78%的ASV符合中性分布，这表明中性过程，即扩散或生态漂移对皮肤微生物区系的迁移贡献最大。此外，中性模型还表明，在冬眠和活动季节阶段，蝙蝠从环境细菌库中主动选择了一些ASV，分别约占总群落的20%和31%。总体而言，这项研究为蝙蝠相关细菌群落的组合提供了洞察力，并将有助于制定针对真菌疾病的保护策略。
Skin microbiota play an important role in protecting bat hosts from the fungal pathogen Pseudogymnoascus destructans, which has caused dramatic bat population declines and extinctions. Recent studies have provided insights into the bacterial communities of bat skin, but variation in skin bacterial community structure in the context of the seasonal dynamics of fungal invasion, as well as the processes that drive such variation, remain largely unexplored. In this study, we characterized bat skin microbiota over the course of the bat hibernation and active season stages and used a neutral model of community ecology to determine the relative roles of neutral and selective processes in driving microbial community variation. Our results showed significant seasonal shifts in skin community structure, as well as less diverse microbiota in hibernation than in the active season. Skin microbiota were influenced by the environmental bacterial reservoir. During both the hibernation and active season stages, more than 78% of ASVs in bat skin microbiota were consistent with neutral distribution, implying that neutral processes, that is, dispersal or ecological drift contributing the most to shifts in skin microbiota. In addition, the neutral model showed that some ASVs were actively selected by the bats from the environmental bacterial reservoir, accounting for approximately 20% and 31% of the total community during hibernation and active season stages, respectively. Overall, this research provides insights into the assemblage of bat‐associated bacterial communities and will aid in the development of conservation strategies against fungal disease.