EVOLUTION OF BUNYAVIRUSES BY GENOME REASSORTMENT IN DUALLY INFECTED MOSQUITOS (AEDES-TRISERIATUS)
EVOLUTION OF BUNYAVIRUSES BY GENOME REASSORTMENT IN DUALLY INFECTED MOSQUITOS (AEDES-TRISERIATUS)
复制标题
DOI：
10.1126/science.4048949
复制
发表时间：
1985-01-01
期刊：
影响因子：
56.9
通讯作者：
BISHOP, DHL
中科院分区：
文献类型：
--
作者：
BEATY, BJ;SUNDIN, DR;BISHOP, DHL
三列伊蚊在同时摄入两种长曲棍球（LAC）病毒突变体后，或在摄入后中断喂食，两种病毒在2天内依次感染后，成为双重感染。经过2周的培养，大约25%的载体含有新的病毒基因型，这是RNA片段重配的结果。当蚊子以老鼠为食时，新的病毒被传播。在最初感染病毒后2天以上摄入的病毒不会引起蚊子媒介的重复感染。
Aedes triseriatus mosquitoes became dually infected after ingesting two mutants of LaCrosse (LAC) virus simultaneously or after ingesting, by interrupted feeding, the two viruses sequentially within a 2-day period. After 2 weeks of incubation, approximately 25 percent of the vectors contained new virus genotypes as the result of RNA segment reassortment. New viruses were transmitted when the mosquitoes fed on mice. Viruses ingested more than 2 days after the initial infecting virus did not cause superinfection of the mosquito vectors.