A General Population Utility Valuation Study For Metastatic Epidural Spinal Cord Compression Health States.
A General Population Utility Valuation Study For Metastatic Epidural Spinal Cord Compression Health States.
复制标题
转移性硬膜外脊髓压迫健康状况的一般人群效用评估研究。
DOI：
10.1097/brs.0000000000002975
复制
发表时间：
2019
期刊：
影响因子：
3
通讯作者：
D. Coyle
中科院分区：
文献类型：
--
作者：
Markian A Pahuta;E. Wai;J. Werier;C. van Walraven;D. Coyle
研究设计
STUDY DESIGN
General population utility valuation study OBJECTIVES.: This study obtained utility valuations from a Canadian general population perspective for 31 unique Metastatic Epidural Spinal Cord Compression (MESCC) health states and determined the relative importance of MESCC-related consequences on quality-of-life.
SUMMARY OF BACKGROUND DATA
Few prospective studies on the treatment of MESCC have collected quality-adjusted-life-year weights (termed "utilities"). Utilities are an important summative measure which distills health outcomes to a single number that can assist healthcare providers, patients, and policy makers in decision making.
METHODS
We recruited a sample of 1138 adult Canadians using a market research company. Quota sampling was used to ensure that the participants were representative of the Canadian population in terms of age, gender, and province of residence. Using the validated MESCC module for the "Self-administered Online Assessment of Preferences" (SOAP) tool, participants were asked to rate 6 of the 31 MESCC health states, each of which presented varying severities of 5 MESCC-related dysfunctions (dependent; non-ambulatory; incontinent; pain; other symptoms).
RESULTS
Participants equally valued all MESCC-related dysfunctions which followed a pattern of diminishing marginal disutility (each additional consequence resulted in a smaller incremental decrease in utility than the previous). These results demonstrate that the general population values physical function equal to other facets of quality-of-life.
CONCLUSIONS
We provide a comprehensive set of ex ante utility estimates for MESCC health states that can be used to help inform decision making. This is the first study reporting direct utility valuation for a spinal disorder. Our methodology offers a feasible solution for obtaining quality-of-life data without collecting generic health status questionnaire responses from patients.
LEVEL OF EVIDENCE
4.