Understanding the Heterogeneity of Human Pericyte Subsets in Blood-Brain Barrier Homeostasis and Neurological Diseases.
Understanding the Heterogeneity of Human Pericyte Subsets in Blood-Brain Barrier Homeostasis and Neurological Diseases.
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作者：
Bohannon DG;Long D;Kim WK
人们越来越认识到周细胞在控制血脑屏障通透性和血管流量方面发挥着重要作用。对这种重要细胞类型的研究因周细胞和其他血管周围细胞类型的表型特性和命名法的广泛混乱而受到阻碍。此外，周细胞异质性和小鼠与人类的物种差异也导致了混乱。在此，我们总结了目前关于识别人类周细胞和周细胞亚群的知识，主要关注人类和非人类灵长类动物的最新发现。人类周细胞和周细胞亚群的精确识别和定义可能有助于我们更好地了解周细胞生物学并开发专门针对与疾病相关的周细胞亚群的新治疗方法。
Pericytes are increasingly recognized as being important in the control of blood–brain barrier permeability and vascular flow. Research on this important cell type has been hindered by widespread confusion regarding the phenotypic identity and nomenclature of pericytes and other perivascular cell types. In addition, pericyte heterogeneity and mouse–human species differences have contributed to confusion. Herein we summarize our present knowledge on the identification of pericytes and pericyte subsets in humans, primarily focusing on recent findings in humans and nonhuman primates. Precise identification and definition of pericytes and pericyte subsets in humans may help us to better understand pericyte biology and develop new therapeutic approaches specifically targeting disease-associated pericyte subsets.
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影响因子：
23.9
作者：
Guimarães-Camboa N;Cattaneo P;Sun Y;Moore-Morris T;Gu Y;Dalton ND;Rockenstein E;Masliah E;Peterson KL;Stallcup WB;Chen J;Evans SM
通讯作者：
Evans SM
影响因子：
5.5
作者：
Birbrair, Alexander;Zhang, Tan;Delbono, Osvaldo
通讯作者：
Delbono, Osvaldo
DOI：
10.1023/a:1011965307612
发表时间：
2001-01-01
期刊：
JOURNAL OF NEUROCYTOLOGY
影响因子：
--
作者：
Bandopadhyay, R;Orte, C;Allt, G
通讯作者：
Allt, G
CNS再髓时，周细胞刺激少突胶质细胞祖细胞分化。
影响因子：
8.8
作者：
De La Fuente AG;Lange S;Silva ME;Gonzalez GA;Tempfer H;van Wijngaarden P;Zhao C;Di Canio L;Trost A;Bieler L;Zaunmair P;Rotheneichner P;O'Sullivan A;Couillard-Despres S;Errea O;Mäe MA;Andrae J;He L;Keller A;Bátiz LF;Betsholtz C;Aigner L;Franklin RJM;Rivera FJ
通讯作者：
Rivera FJ
影响因子：
25
作者：
Damisah EC;Hill RA;Tong L;Murray KN;Grutzendler J
通讯作者：
Grutzendler J