Magnetic resonance imaging of children without sedation: Preparation with simulation

Magnetic resonance imaging of children without sedation: Preparation with simulation
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DOI:
10.1097/00004583-199706000-00024
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发表时间:
1997-06-01
影响因子:
13.3
通讯作者:
Thulborn, KR
Thulborn, KR
中科院分区:
医学1区
文献类型:
--
作者:
Rosenberg, DR;Sweeney, JA;Thulborn, KR

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目的:假设可使用复制磁共振成像(MRI)环境的扫描仪模拟器,使儿科受试者做好准备,成功完成诊断质量的MRI检查,而无需药物镇静。方法:16名6 ~ 17岁的健康儿童与16名未接受过精神药物治疗的强迫症儿童在年龄和性别上相匹配。在整个模拟和扫描过程中,使用心率和自我报告的痛苦量表来测量痛苦。10名6 - 17岁的健康儿童也接受了相同的实际MRI扫描程序,但没有接受模拟扫描程序。结果如下:在模拟器会话期间,在所有受试者中观察到心率和自我报告的痛苦水平显著降低,并保持到实际扫描仪体验结束。所有受试者在没有化学约束的情况下成功完成了MRI检查。未接受模拟器培训的受试者在实际扫描仪中的心率和自我报告的痛苦水平高于接受模拟培训的受试者。结论:在这项初步研究中,无药物镇静的模拟成功地为高质量的MRI研究做好了准备。受试者准备可能是6岁及以上健康和焦虑儿童常规MRI检查镇静的替代程序。
Objective: It was hypothesized that a scanner simulator that replicates the magnetic resonance imaging (MRI) environment could be used to prepare pediatric subjects for successful completion of a diagnostic-quality MRI examination without pharmacological sedation. Method: Sixteen healthy children, 6 to 17 years of age, were matched for age and sex with 16 psychotropic medication-naive children with obsessive-compulsive disorder. Distress was measured throughout simulation and scanning procedures using heart rate and a self-report distress scale. Ten healthy children, 6 to 17 years of age, also underwent the same actual MRI scanning procedure but did not undergo the simulation scanning procedure. Results: Significant decreases in heart rate and self-reported distress level were observed in all subjects during the simulator session that were maintained to the end of the actual scanner experience. All subjects successfully completed MRI examinations without chemical restraint Subjects who were not trained in the simulator had higher heart rates and self-reported distress levels in the actual scanner than did simulation-trained subjects. Conclusions: Simulation without pharmacological sedation successfully prepared pediatric subjects in this pilot study for high-quality MRI studies. Subject preparation may be an alternative procedure to sedation for routine MRI examination in healthy and anxious children 6 years of age and older.