Predictability of intracranial pressure oscillations in patients with suspected normal pressure hydrocephalus by transcranial Doppler ultrasound.
Predictability of intracranial pressure oscillations in patients with suspected normal pressure hydrocephalus by transcranial Doppler ultrasound.
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通过经颅多普勒超声可预测疑似正常压力脑积水患者的颅内压波动。
DOI：
10.1080/01616412.1994.11740261
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发表时间：
1994
影响因子：
1.9
通讯作者：
D. Droste
中科院分区：
文献类型：
--
作者：
J. Krauss;D. Droste
对 36 名疑似有症状的正常压力脑积水 (NPH) 患者进行一晚连续监测，以确定可能从后续分流中受益的患者。通过经颅多普勒超声检查 (TCD) 和 ICP 同时记录其中 33 名患者的大脑中动脉 (MCA) 血流速度。 ICP B 波始终与 TCD 信号（TCD B 波等效）的变化平行。 ICP B 波的相对频率可由 TCD 预测，尽管由于 TCD B 波等效物的相对幅度普遍较低而被略微低估。然而，相同的 TCD B 波等效幅度在不同患者中可能伴随着截然不同的 ICP 变化。考虑到没有压力波时的基线值，不同患者的 ICP 和 TCD 阻力指数 (Pourcelot) 之间没有显着关系。通过向心室注射 10 ml 生理盐水可提高 ICP，但个别患者的 TCD 抵抗指数会增加。由于 B 波活动的相对频率被认为是分流反应性的指标，因此连续 TCD 监测可用作筛查程序，以检测疑似 NPH 患者是否存在 B 波活动及其相对频率。然而，由于绝对ICP和自发振荡幅度都无法预测，TCD监测不适合取代ICP监测。
Intracranial pressure (ICP) was monitored continuously for one night in 36 patients with suspected symptomatic normal pressure hydrocephalus (NPH) to identify patients who might benefit from subsequent shunting. In 33 of these patients middle cerebral artery (MCA) blood flow velocity by means of transcranial Doppler sonography (TCD) and ICP were recorded simultaneously. ICP B-waves always paralleled changes in the TCD signal (TCD B-wave equivalents). The relative frequency of ICP B-waves was predictable by TCD, albeit slightly underestimated due to a generally lower relative amplitude of the TCD B-wave equivalents. However, the same TCD B-wave equivalent amplitude could be accompanied by quite different ICP changes in different patients. Considering the baseline values in the absence of pressure waves, there was no significant relationship between ICP and TCD resistance index (Pourcelot) in different patients. Raising ICP by injection of 10 ml saline into the ventricle, however was accompanied by an increased TCD resistance index in the individual patient. As the relative frequency of B-wave activity is assumed to be an indicator for shunt responsiveness, continuous TCD monitoring can be used as a screening procedure to detect the presence and the relative frequency of B-wave activity in patients with suspected NPH. However, since neither the absolute ICP nor the amplitude of spontaneous oscillations can be predicted, TCD monitoring is not suitable to replace ICP monitoring.
脑脊液分流治疗痴呆、失禁和步态障碍。
DOI：
--
发表时间：
1985
期刊：
Clinical neurosurgery
影响因子：
--
作者：
Black,PM;Ojemann,RG;Tzouras,A
通讯作者：
Tzouras,A