Relationship between individual categories of adverse childhood experience and diabetes in adulthood in a sample of US adults: Does it differ by gender?
Relationship between individual categories of adverse childhood experience and diabetes in adulthood in a sample of US adults: Does it differ by gender?
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DOI：
10.1016/j.jdiacomp.2017.11.005
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发表时间：
2018-02-01
影响因子：
3
通讯作者：
Egede, Leonard
中科院分区：
文献类型：
--
作者：
Campbell, Jennifer A.;Farmer, Gail C.;Egede, Leonard
目的：已知ACE会增加成年糖尿病的风险。然而，很少有人知道个别ACE类别对糖尿病风险的差异性影响，以及这种关系是否是性别特异性的。方法：2011年BRFSS的数据在这项研究中使用。参与者包括48，526名成年人，他们在5个州完成了ACE模块。使用logistic回归，我们研究了与八种ACE相关的成年糖尿病的几率：性虐待，身体虐待，言语虐待，精神疾病，药物滥用，监禁，分居/离婚和暴力。一个性别的相互作用的长期测试，如果这种关系在男性和women.Results之间变化：在调整后的分析，性虐待（OR 1.57，CI 1.240; 1.995）有最强的正相关，其次是口头（OR 1.29，CI 1.117; 1.484）和身体虐待（OR 1.26，CI 1.040; 1.516）。父母有精神疾病也与糖尿病的几率增加显著相关（OR 1.19，CI 0.996; 1.416）。ACE和糖尿病状态之间没有相互作用的性别在任何的八个categories werened.Conclusions：总体而言，这项研究发现，四个ACE类别显着相关性虐待是最强的预测因素与成年糖尿病的几率增加。(C)2017爱思唯尔公司All rights reserved.
Aims: ACEs are known to increase risk for diabetes in adulthood. However, little is known about the differential impact of individual ACE categories on diabetes risk, and whether this relationship is gender specific.Methods: Data from the 2011 BRFSS was used in this study. Participants included 48,526 adults who completed the ACE module across 5 states. Using logistic regression, we examined the odds of diabetes in adulthood related to eight individual categories of ACEs: sexual abuse, physical abuse, verbal abuse, mental illness, substance abuse, incarceration, separation/divorce, and violence. A gender interaction term was included to test if this relationship varied between men and women.Results: In adjusted analyses, sexual abuse (OR 1.57, CI 1.240; 1.995) had the strongest positive association followed by verbal (OR 1.29, CI 1.117; 1.484) and physical abuse (OR 1.26, CI 1.040; 1.516). Having a parent with mental illness was also significantly associated with increased odds of diabetes (OR 1.19, CI 0.996; 1.416). No interaction between ACEs and diabetes status by gender in any of the eight categories was found.Conclusions: Overall, this study found that four ACE categories were significantly associated with increased odds of diabetes in adulthood with sexual abuse being the strongest predictor. (C) 2017 Elsevier Inc. All rights reserved.