Sonographic diagnosis for Mikulicz disease
Sonographic diagnosis for Mikulicz disease
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DOI：
10.1016/j.tripleo.2009.02.032
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发表时间：
2009-07-01
期刊：
影响因子：
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通讯作者：
Yoshiura, Kazunori
中科院分区：
文献类型：
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作者：
Shimizu, Mayumi;Moriyama, Masafumi;Yoshiura, Kazunori
Objective.目的是探讨Mikulicz病（MD）的影像学诊断特征，特别是超声特征，并阐明它们与干燥综合征（SS）之间的差异，基于MD的新标准。研究设计。对9例符合MD诊断标准的患者的超声、涎腺造影、临床、组织病理学及血清学检查结果进行分析，并与SS进行比较。所有肿胀的下颌下腺在超声图像上显示双侧结节低回声区伴高血管化，在涎腺造影上显示实质缺损，而腮腺在两种图像上均显示正常或轻微变化。计算机断层扫描和磁共振成像下颌下腺超声图像中的结节区域不清楚，但镓层析成像显示积聚。Mikulicz病表现为双侧下颌下腺淋巴结改变率高，与SS完全不同。对于这些变化的检测和随访，超声检查可能是最好的成像方式。(Oral口腔外科医学口腔病理学口腔放射学Endod 2009; 108：105-113）
Objective. The aim was to investigate the diagnostic imaging characteristics of Mikulicz disease (MD), especially sonographic ones, and to clarify the differences between them and those in Sjogren syndrome (SS), based on new criteria of MD.Study design. The sonographic and sialographic images, as well as clinical, histopathologic, and serologic findings of 9 patients satisfying the new criteria of MD were analyzed and compared with those in SS.Results. All swollen submandibular glands showed bilateral nodal hypoechoic areas with high vascularization on sonograms and a parenchymal defect on sialograms, whereas parotid glands showed normal or slight change on both images. Nodal areas in submandibular gland sonograms were unclear on computerized tomography and on magnetic resonance imaging, but showed accumulation on gallium scintigraphy.Conclusion. Mikulicz disease showed a high rate of bilateral nodal change in submandibular glands, which was completely different from SS. For detection and follow-up of these changes, sonography may be the best imaging modality. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009; 108: 105-113)