Origin of ciliated craniopharyngioma: pathological relationship between Rathke cleft cyst and ciliated craniopharyngioma.
Origin of ciliated craniopharyngioma: pathological relationship between Rathke cleft cyst and ciliated craniopharyngioma.
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纤毛性颅咽管瘤的起源：Rathke裂囊肿与纤毛性颅咽管瘤的病理关系。
DOI：
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发表时间：
1995
期刊：
影响因子：
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通讯作者：
K. Fujii
中科院分区：
文献类型：
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作者：
H. Oka;N. Kawano;S. Yagishita;T. Suwa;T. Yoshida;H. Maezawa;S. Utsuki;T. Kameya;K. Fujii
为了解纤毛性颅咽管瘤的起源，对纤毛性颅咽管瘤和Rathke裂囊肿进行了组织学研究。研究对象为7例症状性Rathke裂囊肿和1例纤毛性颅咽管瘤。对8例手术切除标本进行光镜和电子显微镜观察。纤毛型颅咽管瘤主要由乳头型颅咽管瘤和散在的纤毛柱状上皮组成，包括杯状细胞。4例Rathke裂囊肿表现为鳞状化生，其基底细胞形态与乳头型颅咽管瘤相似。Rathke裂囊肿3例，可见基底细胞有张力纤维和桥粒。纤毛性颅咽管瘤可能来源于Rathke裂隙上皮的基底层细胞。
Histological study was undertaken on ciliated craniopharyngioma and Rathke cleft cyst, to know the origin of ciliated craniopharyngioma. Subjects were 7 cases with symptomatic Rathke cleft cysts and a ciliated craniopharyngioma. Light and electron microscopic observations were made on surgically resected specimens of the 8 cases. The ciliated craniopharyngioma was composed mainly of papillary type of craniopharyngioma and of dispersed ciliated columnar epithelium including goblet cells. Four cases with Rathke cleft cyst showed squamous metaplasia of which the basal cells were histologically similar to that of papillary type of craniopharyngioma. Other 3 cases of Rathke cleft cyst, basal cells were revealed to have tonofilaments and desmosomes. It seems possible that ciliated craniopharyngioma has derived from the basal cells of Rathke cleft epithelium.