Laser ablation inductively coupled plasma mass spectrometric transient signal data acquisition and analyte concentration calculation
Laser ablation inductively coupled plasma mass spectrometric transient signal data acquisition and analyte concentration calculation
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DOI：
10.1039/ja9961100899
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发表时间：
1996-09-01
影响因子：
3.4
通讯作者：
Gunther, D
中科院分区：
文献类型：
--
作者：
Longerich, HP;Jackson, SE;Gunther, D
激光烧蚀电感耦合等离子体质谱（LA-ICP-MS）产生复杂的、随时间变化的信号，这些信号在数据采集和还原过程中需要与溶液样品引入产生的稳态信号有明显不同的处理方法。本文详细讨论了LA-ICP-MS分析中数据采集和简化的考虑，提出了最佳数据采集参数，推导了采用时间分辨数据采集时样品浓度和LOD的计算公式，从已知分析物浓度的参考物质中获得灵敏度校准，并使用天然存在的内标对漂移的乘法校正因子进行校正。基体效应和材料烧蚀和输送到ICP的量。
Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) produces complex, time-dependent signals, These require significantly different treatment both during data acquisition and reduction from the more steady-state signals produced by solution sample introduction. This paper discusses, in detail, data acquisition and reduction considerations in LA-ICP-MS analysis, Optimum data acquisition parameters are suggested, Equations are derived for the calculation of sample concentrations and LOD when time-resolved data acquisition is employed, sensitivity calibration is obtained from reference materials with known analyte concentrations and naturally occurring internal standards are used to correct for the multiplicative correction factors of drift, matrix effects and the amount of material ablated and transported to the ICP.