The origin and fate of the urethral plate in man.
The origin and fate of the urethral plate in man.
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DOI：
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发表时间：
1954-07
影响因子：
2.4
通讯作者：
BY T. W. Glenister;Charing Cross;T. Glenister
中科院分区：
文献类型：
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作者：
BY T. W. Glenister;Charing Cross;T. Glenister
除了 Barnstein & Mossman (1938) 之外，该问题的研究者一致认为尿道板是泄殖腔和泌尿生殖窦壁的产物。一些工作者（Debierre，1883；Tourneux，1889；Schwartztrauber，1904；Lichtenberg，1906）认为尿道板发育的区域是外胚层起源的，因此尿道板和整个阴茎尿道都源自外胚层。其他人（Herzog，1904；Felix，1912；Johnson，1920；Williams，1952）认为泌尿生殖窦是内胚层衍生物。因此，根据这些作者的说法，尿道板和由此产生的腺尿道是内胚层起源的，阴茎尿道的其余部分是从泌尿生殖窦本身发育而来的。 Van den Broeck (1909) 同意尿道板起源于内胚层，但认为它有助于阴茎尿道所有部分的衬里，并且覆盖尿道皱襞的表面上皮被纳入尿道底。 Siddiqi (1937)认为尿道板的背侧部分由泌尿生殖窦发育而来，而腹侧部分则源自外胚层泄殖腔。因此，尿道球部腺、球部、尿道近端三分之二的底部和整个远端三分之一是外胚层的，但尿道近端三分之二的顶部纯粹是内胚层起源的。 Berry Hart (1908) 和 Wood Jones (1910, 1914) 认为腺体尿道是由外胚层细胞索的管化产生的，该细胞连接海绵状尿道的管腔，而海绵状尿道本身源自内胚层组织。 Barnstein & Mossman (1938) 阐明了一个完全不同的概念。根据他们的说法，尿道板是从尿道沟沿着阴茎下表面向内生长的外胚层。该外胚层产生整个阴茎尿道和球尿道腺。
Apart from Barnstein & Mossman (1938) investigators of this problem agree that the urethral plate is an outgrowth from the walls of the cloaca and of the urogenital sinus. Some workers (Debierre, 1883; Tourneux, 1889; Schwartztrauber, 1904; Lichtenberg, 1906) consider that the region from which the urethral plate develops is of ectodermal origin, and consequently the urethral plate and the whole penile urethra are derived from ectoderm. Others (Herzog, 1904; Felix, 1912; Johnson, 1920; Williams, 1952) believe that the urogenital sinus is an endodermal derivative. Consequently according to these authors, the urethral plate and the resulting glandar urethra are of endodermal origin, the remainder of the penile urethra developing from the urogenital sinus itself. Van den Broeck (1909) agrees that the urethral plate is of endodermal origin, but considers that it contributes to the lining of all parts of the penile urethra, and that surface epithelium covering the urethral folds is incorporated into the floor of the urethra. Siddiqi (1937) considers that the dorsal half of the urethral plate develops from the urogenital sinus, whereas the ventral part is derived from the ectodermal cloaca. Thus the bulbo-urethral glands, the bulb, the floor of the proximal two-thirds and the whole of the distal third of the urethra are ectodermal, but the roof of the proximal two-thirds of the urethra is purely endodermal in origin. Berry Hart (1908) and Wood Jones (1910, 1914) suggest that the glandar urethra results from the canalization of an ectodermal cord of cells which joins the lumen of the spongy urethra, itself derived from endodermal tissue. Barnstein & Mossman (1938) have enunciated a completely different concept. According to them, the urethral plate develops as an ectodermal ingrowth from the urethral groove along the under surface of the phallus. This ectodermal lamina gives rise to the whole penile urethra and the bulbo-urethral glands.