The natural history of new-onset heart failure with a severely depressed left ventricular ejection fraction: Implications for timing of implantable cardioverter-defibrillator implantation

The natural history of new-onset heart failure with a severely depressed left ventricular ejection fraction: Implications for timing of implantable cardioverter-defibrillator implantation
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DOI:
10.1016/j.ahj.2012.06.009
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发表时间:
2012-09-01
影响因子:
4.8
通讯作者:
Drazner, Mark H.
Drazner, Mark H.
中科院分区:
医学2区
文献类型:
--
作者:
Teeter, William A.;Thibodeau, Jennifer T.;Drazner, Mark H.

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背景指南建议新发的收缩性心力衰竭(HF)患者在植入心脏除颤器(ICD)之前接受药物治疗试验。这一策略可以改善左心室射血分数(LVEF),从而避免ICD,但在药物治疗试验期间,患者面临潜在的可预防的心脏性猝死的风险。
Background Guidelines recommend that patients with new-onset systolic heart failure (HF) receive a trial of medical therapy before an implantable cardiac defibrillator (ICD). This strategy allows for improvement of left ventricular ejection fraction (LVEF), thereby avoiding an ICD, but exposes patients to risk of potentially preventable sudden cardiac death during the trial of medical therapy.Methods We reviewed a consecutive series of patients with HF of