Nycthemeral variation in thermal dehydration-induced thirst.
Nycthemeral variation in thermal dehydration-induced thirst.
复制标题
热脱水引起的口渴的夜间变化。
DOI：
10.1016/0031-9384(95)00059-r
复制
发表时间：
1995
影响因子：
2.9
通讯作者：
Meeuwsen,KW
中科院分区：
文献类型：
--
作者：
Barney,CC;Vergoth,C;Renkema,LA;Meeuwsen,KW
大鼠自发饮水量的时间变化已经确定，但对脱水后饮水量的时间变化知之甚少。在本研究中，不同的雄性Sprague-Dawley大鼠每4小时在25°C或40°C的环境中无水暴露3小时，持续20小时。然后让大鼠在25°C的环境中取水2小时。暴露在25°C的大鼠在蒸发失水、尿量、尿钠和尿钾排泄、水摄入量和补液百分比方面表现出显著的时间变化，夜间的数值更高。与25℃环境相比，40℃环境下大鼠蒸发失水、尿钠排泄量、粪便排出量和饮水量均显著增加，且时间变化与25℃环境相似。热脱水对大鼠水分平衡的强大影响是与一天中时间的影响加在一起的，而不是相互作用的。
Temporal variation in spontaneous water intake in rats is well established but little is known about temporal variation in water intake following dehydration. In the present study different male Sprague-Dawley strain rats were exposed without water for 3 h to either a 25°C or a 40°C environment every 4 h for 20 h. The rats were then allowed access to water in a 25°C environment for 2 h. Rats exposed to 25°C showed significant temporal variation in evaporative water loss, urine output, urine sodium and potassium excretion, water intake, and percent rehydration with higher values occurring during the night. Rats exposed to 40°C had greater evaporative water loss, urine sodium excretion, feces output and water intake than the rats exposed to 25°C and had temporal variations which were similar to those of the rats exposed to 25°C. The robust effects of thermal-dehydration on water balance in rats are additive to rather than interactive with the effects of time of day.