Increase of antibody titer against Leucocytozoon caulleryi by oral administration of recombinant R7 antigen
Increase of antibody titer against Leucocytozoon caulleryi by oral administration of recombinant R7 antigen
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DOI：
10.1292/jvms.67.211
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发表时间：
2005-02-01
影响因子：
1.2
通讯作者：
Matsumura, T
中科院分区：
文献类型：
--
作者：
Ito, A;Gotanda, T;Matsumura, T
在这项研究中，我们用鸡白细胞人畜共患病亚单位疫苗（LV）接种和未接种的鸡口服了大肠杆菌中表达的重组R7 （rR7）抗原。只有接种lv疫苗的鸡再次产生抗第二代分裂体（2GS）抗体。抗2gs抗体滴度为中等水平的lv接种鸡经R7抗原口服后，其抗2gs抗体滴度较接种对照鸡明显升高（P < 0.01, P < 0.05）。
In this study, we examined oral administration with recombinant R7 (rR7) antigen expressed in Escherichia coli using chicken leucocytozoonosis subunit vaccine (LV)-vaccinated and unvaccinated chickens. Only LV-vaccinated chickens showed re-induction of anti-second-generation schizont (2GS) antibody. Also, LV-vaccinated chickens whose anti-2GS antibody titer was middle-level showed increases of the antibody titer compared to vaccinated-control chickens (P>0.01, >0.05) after oral administration with R7 antigen.