Antimicrobial resistance in isolates from inpatients and outpatients in the united states: Increasing importance of the intensive care unit
Antimicrobial resistance in isolates from inpatients and outpatients in the united states: Increasing importance of the intensive care unit
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DOI：
10.1093/clinids/24.2.211
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发表时间：
1997-02-01
影响因子：
11.8
通讯作者：
Gaynes, R
中科院分区：
文献类型：
--
作者：
Archibald, L;Phillips, L;Gaynes, R
为了比较医院和社区的耐药率，我们分析了美国8家医院住院和门诊患者分离的细菌的耐药率，结果显示：甲氧西林/凝固酶阴性葡萄球菌(分别为49.0%和36.0%)、甲氧西林/金黄色葡萄球菌(分别为33.0%和14.5%)、头孢他啶/阴沟肠杆菌(分别为26.0%和12.0%)、头孢他啶/阴沟肠杆菌(分别为26.0%和12.0%)；P<；.01)；亚胺培南/铜绿假单胞菌(12.0%比6.5%；P<；0.01)；头孢他啶/铜绿假单胞菌(7.8%比4.0%；P<；0.01)；.01)，从重症监护病房(ICU)、非ICU住院患者和门诊患者分离的耐药菌百分比显著下降，这些结果表明，分配给控制耐药性的资源应继续集中在医院，特别是ICU。
To compare the occurrence of antimicrobial resistance in hospitals with that in the community, we analyzed data for isolates collected from inpatients and outpatients in eight U.S. hospitals, The percentage of resistant isolates from inpatients was higher than that from outpatients for the following combinations of antimicrobials and organisms: methicillin/coagulase-negative Staphylococcus (49.0% vs. 36.0%, respectively; P < .01); methicillin/Staphylococcus aureus (33.0% vs. 14.5%, respectively; P < .01); ceftazidime/Enterobacter cloacae (26.0% vs. 12.0%, respectively; P < .01); imipenem/Pseudomonas aeruginosa (12.0% vs. 6.5%, respectively; P < .01); ceftazidime/P. aeruginosa (7.8% vs. 4.0%, respectively; P < .01); and vancomycin/Enterococcus species (6.3% vs. 1.4%, respectively; P < .01), There was a significant stepwise decrease in the percentage of resistant organisms isolated from patients in the intensive care unit (ICU), non-ICU inpatients, and outpatients, These results suggest that resources allocated to control antimicrobial resistance should continue to be focused in the hospital, particularly in the ICU.