Consistent pulmonary and systemic responses from inhalation of fine concentrated ambient particles: Roles of rat strains used and physicochemical properties

Consistent pulmonary and systemic responses from inhalation of fine concentrated ambient particles: Roles of rat strains used and physicochemical properties
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吸入高浓度环境微粒会产生一致的肺部和全身反应: 所用大鼠品系和理化特性的作用

DOI:
10.1289/ehp.7868
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发表时间:
2005-11-01
影响因子:
10.4
通讯作者:
Costa, DL
Costa, DL
中科院分区:
环境科学与生态学1区
文献类型:
--
作者:
Kodavanti, UP;Schladweiler, MC;Costa, DL

文献摘要

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Several studies have reported health effects of concentrated ambient particles (CALP) in rodents and humans; however, toxicity end points in rodents have provided inconsistent results. In 2000 we conducted six 1-day exposure studies where spontaneously hypertensive (SH) rats were exposed to filtered air or CAPs (