RESURGENCE OF TUBERCULOSIS IN CHILDREN
RESURGENCE OF TUBERCULOSIS IN CHILDREN
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DOI：
10.1016/s0022-3476(05)81949-3
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发表时间：
1992-06-01
影响因子：
5.1
通讯作者：
JEREB, J
中科院分区：
文献类型：
--
作者：
STARKE, JR;JACOBS, RF;JEREB, J
尽管在诊断技术和治疗有效性方面取得了一定的进展，但结核分枝杆菌仍然是全世界引起最多慢性疾病和死亡的病原体之一。世界上超过20%的人口感染了结核杆菌。每年有800万至1 000万新病例和300万至500万人死于结核病。1发展中国家15岁以下儿童每年有130万例结核病病例和45万例死亡。2直到最近，世界卫生组织和各国政府才认识到这种疾病的巨大经济影响。[3]在发病率持续下降数十年之后，美国结核病正在显著复苏。1990年，25 000多名成人和儿童患上结核病。1987年至1990年，美国5岁以下儿童的结核病病例增加了39%。从历史上看，当人口受到战争、流离失所、营养不良和医疗保健不足等压力时，结核病发病率就会增加。
Despite modest advances in diagnostic techniques and effectiveness of treatment, Mycobacterium tuberculosis remains one of the pathogens causing the greatest amount of chronic disease and death throughout the world. More than 20% of the world's population is infected with the tubercle bacillus. Every year, there are 8 to 10 million new cases and 3 to 5 million deaths attributed to tuberculosis. 1 Children less than 15 years of age in developing countries have 1.3 million cases and 450,000 deaths annually from tuberculosis. 2 Only recently has the enormous economic impact of this disease been appreciated by the World Health Organization and national governments. 3 After decades of consistently declining incidence, a remarkable resurgence of tuberculosis is occurring in the United States. In 1990, tuberculous disease developed in more than 25,000 adults and children. Between 1987 and 1990 the number of tuberculosis cases among children less than 5 years of age increased 39% in the United States. Historically, tuberculosis case rates have increased when populations have been exposed to stresses such as war, displacement, poor nutrition, and inadequate health care.