Crystallization of the Staphylococcus aureus MazF mRNA interferase.
Crystallization of the Staphylococcus aureus MazF mRNA interferase.
复制标题
金黄色葡萄球菌 MazF mRNA 干扰酶的结晶。
DOI：
10.1107/s1744309111000571
复制
发表时间：
2011
期刊：
影响因子：
--
通讯作者：
Loris,Remy
中科院分区：
文献类型：
--
作者：
Zorzini,Valentina;Haesaerts,Sarah;Donegan,NilesP;Fu,Zhibiao;Cheung,AmbroseL;vanNuland,NicoAJ;Loris,Remy
mazEF modules encode toxin–antitoxin pairs that are involved in the bacterial stress response through controlled and specific degradation of mRNA. Staphylococcus aureus MazF and MazE constitute a unique toxin–antitoxin module under regulation of the sigB operon. A MazF-type mRNA interferase is combined with an antitoxin of unknown fold. Crystals of S. aureus MazF (SaMazF) were grown in space group P212121. The crystals diffracted to 2.1 Å resolution and are likely to contain two SaMazF dimers in the asymmetric unit.
