Joint effects of adiposity and physical activity on incident mobility limitation in older adults
Joint effects of adiposity and physical activity on incident mobility limitation in older adults
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DOI：
10.1111/j.1532-5415.2007.01632.x
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发表时间：
2008-04-01
影响因子：
6.3
通讯作者：
Harris, Tamara B.
中科院分区：
文献类型：
--
作者：
Koster, Annemarie;Patel, Kushang V.;Harris, Tamara B.
目的：研究体力活动和肥胖测量（身体质量指数（BMI）、腰围、体脂百分比）与活动受限的联合关系。设计：前瞻性观察队列研究。周边环境：田纳西州孟菲斯市和宾夕法尼亚州匹兹堡市。参与者：参与健康、衰老和身体组成（Health ABC）研究的2,982名年龄在70至79岁之间的黑人和白人男性和女性。测量：活动受限的定义是在6.5年以上的连续两次半年评估中报告行走四分之一英里或爬10级台阶的困难。这项研究包括了三种肥胖的测量方法：身体质量指数、总体脂百分比和腰围。身体活动评估采用改进的休闲时间身体活动问卷。结果：46%的队列出现活动受限。高BMI （>= 30 kg/m(2)）、高总体脂率（>= 31.3%）或高腰围（>= 102 cm）的白人和黑人男性发生活动受限的风险分别比低脂肪者高约60%、40%和40%。在女性中，与低肥胖人群相比，高肥胖人群的活动受限风险也明显更高。在所有组中，低体力活动（最低四分位数）与活动受限风险增加70%相关。高肥胖和低体力活动的人活动受限的风险特别高。经常运动的高肥胖人群与不运动的低肥胖人群发生活动受限的风险是一样高的。结论：在功能良好的老年人中，高脂肪和低自我报告的体力活动预示着活动受限的发生。因此，预防老年体重增加和促进肥胖和非肥胖老年人的身体活动可能是预防行动能力丧失和未来残疾的有效策略。
OBJECTIVES: To examine joint associations of physical activity and adiposity measures (body mass index (BMI), waist circumference, percentage body fat) with incident mobility limitation.DESIGN: Prospective observational cohort study.SETTING: Memphis, Tennessee and Pittsburgh, Pennsylvania.PARTICIPANTS: Two thousand nine hundred and eighty-two black and white men and women aged 70 to 79 participating in the Health, Aging and Body Composition (Health ABC) study.MEASUREMENTS: Mobility limitation was defined as reported difficulty walking one-quarter of a mile or climbing 10 steps during two consecutive semiannual assessments over 6.5 years. Three measures of adiposity were included in this study: BMI, total percentage body fat, and waist circumference. Physical activity was assessed using a modified leisure-time physical activity questionnaire.RESULTS: Forty-six percent of the cohort developed mobility limitation. White and black men with a high BMI (>= 30 kg/m(2)), high total percentage body fat (>31.3%), or high waist circumference (>= 102 cm) had an approximately 60%, 40%, and 40%, respectively, higher risk of incident mobility limitation than those with low adiposity. In women, high adiposity was also associated with a significantly higher mobility limitation risk than in those with low adiposity. Low physical activity (lowest quartile) was associated with a 70% higher risk of mobility limitation in all groups. Persons with high adiposity and low physical activity were at particularly high risk of mobility limitation. People with high adiposity who were physically active had an equally high risk of mobility limitation as inactive people with low adiposity.CONCLUSION: High adiposity and low self-reported physical activity predicted the onset of mobility limitation in well-functioning older persons. Preventing weight gain in old age and promoting physical activity in obese and non-obese older persons may therefore be effective strategies to prevent mobility loss and future disability.