Is stroke the most common cause of disability?
Is stroke the most common cause of disability?
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DOI：
10.1016/j.jstrokecerebrovasdis.2004.06.003
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发表时间：
2004-07-01
期刊：
影响因子：
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通讯作者：
Ebrahim, Shah
中科院分区：
文献类型：
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作者：
Adamson, Joy;Beswick, Andy;Ebrahim, Shah
背景：人们普遍认为中风是导致严重残疾的最常见原因。我们的目的是研究这种说法是否支持任何evidence.METHODS：我们进行了二次分析，国家统计局1996年残疾调查，英国。这是一个多阶段分层随机抽样的8683非制度化的个人，年龄在16岁和101岁之间，平均62岁，响应率83%（n = 8816）。使用的结果是人口普查和调查办公室的残疾严重程度量表。比值比和人口归因分数进行计算，以检查诊断和disability.RESULTS之间的关联：Logistic回归模型表明，调整后的合并症和年龄，那些中风有最高的赔率报告严重的整体残疾（比值比4.88，95%置信区间[CI] 3.37-6.10）。中风也与更多的个人领域的残疾比任何其他条件考虑。调整后的人群归因分数也进行了计算，并表明肌肉骨骼疾病的人群归因分数最高（30.3%，95% CI 26.2-34.1），其次为精神障碍（8.2%，95%CI6.9 -9.5）和中风（4.5%，95%CI3.6 -5.3）。结论：中风不是英国非住院人群中最常见的残疾原因。然而，中风与报告严重残疾的几率最高相关。重要的是，与其他疾病相比，中风与更多的残疾领域相关，可能被认为是复杂残疾的最常见原因。
BACKGROUND: It is widely stated that stroke is the most common cause of severe disability. We aimed to examine whether this claim is supported by any evidence.METHODS: We conducted secondary analysis of the Office of National Statistics 1996 Survey of Disability, United Kingdom. This was a multistage stratified random sample of 8683 noninstitutionalized individuals aged between 16 and 101 years, mean 62 years, response rate 83% (n = 8816). The outcome used was the Office of Population Censuses and Surveys severity scale for disability. Odds ratios and population-attributable fractions were calculated to examine the associations between diagnoses and disability.RESULTS: Logistic regression modelling suggests that, after adjustment for comorbidity and age, those with stroke had the highest odds of reporting severe overall disability (odds ratio 4.88, 95% confidence interval [CI] 3.37-6.10). Stroke was also associated with more individual domains of disability than any of the other conditions considered. Adjusted population-attributable fractions were also calculated and indicated that musculoskeletal disorders had the highest population-attributable fraction (30.3%, 95% CI 26.2-34.1) followed by mental disorders (8.2%, 95% CI 6.9-9.5) and stroke (4.5%, 95% CI 3.6-5.3).CONCLUSION: Stroke is not the most common cause of disability among the noninstitutionalized United Kingdom population. However, stroke is associated with the highest odds of reporting severe disability. Importantly, stroke is associated with more individual domains of disability compared with other conditions and might be considered to be the most common cause of complex disability.