Recent progress in the understanding and treatment of nonepileptic seizures
Recent progress in the understanding and treatment of nonepileptic seizures
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DOI：
10.1097/yco.0b013e3283523db6
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发表时间：
2012-05
影响因子：
6.9
通讯作者：
M. Reuber;R. Mayor
中科院分区：
文献类型：
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作者：
M. Reuber;R. Mayor
综述的目的在过去的二十年里，关于（心因性）非癫痫性发作（内斯）的出版物数量稳步增加。本文主要介绍近三年来发表的论文。本文就内斯的诊断、病因、临床表现及治疗等方面的最新进展作一综述。最近的研究结果最近的几项研究表明，范围和局限性的基于神经网络和会话分析方法的癫痫和内斯的鉴别诊断。实验工作已经揭示，内斯患者在休息时的生理唤醒水平增加，这与异常的心理处理有关。人们对内斯的异质性表现的意义和临床意义有了越来越多的认识。几项研究记录了早期有效沟通内斯诊断的治疗潜力。一些随机对照或非对照的长期随访试点研究表明，不同形式的心理治疗对内斯有效。摘要最近的研究提高了我们对内斯作为一种生物心理社会障碍的理解。内斯患者明确的诊断和管理途径很可能在不久的将来出现。
Purpose of review There has been a steady increase in the number of publications about (psychogenic) nonepileptic seizures (NES) over the past two decades. This review focuses on work published in the past 3 years. It summarizes the most important developments in terms of diagnosis, cause, clinical manifestations and treatment of NES. Recent findings Several recent studies demonstrate the scope and limitation of questionnaire-based and conversation analytic approaches to the differential diagnosis of epilepsy and NES. Experimental work has revealed that patients with NES have increased levels of physiological arousal at rest which are associated with abnormal mental processing. There is a growing understanding of the meaning and clinical significance of the heterogeneous manifestations of NES. Several studies document the therapeutic potential of an early and effective communication of the diagnosis of NES. A number of randomized controlled or uncontrolled long-term follow-up pilot studies suggest that different forms of psychotherapy are effective for NES. Summary Recent research has improved our understanding of NES as a biopsychosocial disorder. Clear diagnostic and management pathways for patients with NES are likely to emerge in the near future.