Highly Enantioselective Cyclopropenation Reaction of 1-Alkynes with α-Alkyl-α-Diazoesters Catalyzed by Dirhodium(II) Carboxylates
Highly Enantioselective Cyclopropenation Reaction of 1-Alkynes with α-Alkyl-α-Diazoesters Catalyzed by Dirhodium(II) Carboxylates
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DOI：
10.1002/anie.201101905
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发表时间：
2011-01-01
影响因子：
16.6
通讯作者：
Hashimoto, Shunichi
中科院分区：
文献类型：
--
作者：
Goto, Takayuki;Takeda, Koji;Hashimoto, Shunichi
两个铑（II）离子一起工作：[Rh 2（S-tbpttl）4]是一种非常有效的催化剂，用于1-炔与α-烷基-α-重氮乙酸酯的对映选择性环丙烯化反应（见示意图）。环丙烯化优于通过1，2-氢化物移位形成烯烃。
Two rhodium (II) ions work together:[Rh 2 (S-tbpttl) 4] is an exceptionally effective catalyst for enantioselective cyclopropenation reactions of 1-alkynes with α-alkyl-α-diazoacetates (see scheme). Cyclopropenation is preferred over alkene formation through a 1, 2-hydride shift.