Ocular Axial Length and Its Associations in an Adult Population of Central Rural India: The Central India Eye and Medical Study
Ocular Axial Length and Its Associations in an Adult Population of Central Rural India: The Central India Eye and Medical Study
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DOI：
10.1016/j.ophtha.2009.11.040
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发表时间：
2010-07-01
期刊：
影响因子：
13.7
通讯作者：
Panda-Jonas, Songhomitra
中科院分区：
文献类型：
--
作者：
Nangia, Vinay;Jonas, Jost B.;Panda-Jonas, Songhomitra
目的：调查的地球仪，这是一个主要的测量眼睛的轴长的正态分布，其与其他眼睛和系统的parameters.Design：人口为基础的study.Participants：印度中部的眼睛和医学研究是一个人口为基础的研究在印度中部的农村地区进行。该研究包括4711名受试者（年龄30岁以上）的5885个合格的个人（响应率，80.1%）。轴向长度测量sonographic.Main结果措施：轴向length.Results：轴向长度测量4698研究参与者（99.7%）。他们的平均年龄为49.4 ± 13.4岁（范围：30-100岁），平均屈光不正为-0.18 ± 1.48屈光度（范围：-20.0至+7.25屈光度）。平均轴向长度为22.6 ± 0.91 mm（范围：18.22-34.20 mm）。在多变量分析中，眼轴长度与年龄增加、身高增加、身体质量指数增加和教育水平提高等全身参数显著相关（P < 0.001），与最佳矫正视力降低、角膜屈光力降低、前房加深、透镜增厚、近视球镜屈光力和柱镜屈光力增加等眼部参数显著相关（P < 0.001）。在高度近视组中，定义为眼轴长度超过26.5 mm，（眼轴长度与球镜屈光力之间的相关性除外）有统计学意义在单因素或多因素分析中，P > 0.15。在印度中部的农村人群中，平均眼轴长度为22.6 ± 0.91 mm，比其他人群短。眼轴长度与年龄增加、身高增加、身体质量指数增加和教育水平提高等全身参数相关，与最佳矫正视力降低、角膜屈光力降低、前房加深、透镜增厚和近视球镜和柱镜屈光力增加等眼部参数相关。这些关联仅对那些非高度近视的眼睛有效，而眼轴长度仅在高度近视的眼睛中与屈光不正相关。Ophthalmology 2010; 117：1360-1366（C）2010，美国眼科学会。
Purpose: To investigate the normal distribution of axial length of the globe, which is a major measurement of the eye, and its associations with other ocular and systemic parameters.Design: Population-based study.Participants: The Central India Eye and Medical Study is a population-based study performed in a rural region of central India. The study comprised 4711 subjects (aged 30+ years) of 5885 eligible individuals (response rate, 80.1%).Methods: A detailed ophthalmic and medical examination was performed. The axial length was measured sonographically.Main Outcome Measures: Axial length.Results: Axial length measurements were available on 4698 study participants (99.7%). Their mean age was 49.4 +/- 13.4 years (range, 30-100 years), and the mean refractive error was -0.18 +/- 1.48 diopters (range, -20.0 to +7.25 diopters). Mean axial length was 22.6 +/- 0.91 mm (range, 18.22-34.20 mm). In multivariate analysis, axial length was significantly (P < 0.001) associated with the systemic parameters of increased age, taller body height, greater body mass index, and higher level of education, and with the ocular parameters of lower best-corrected visual acuity, lower corneal refractive power, deeper anterior chamber, thicker lens, and more myopic spherical power and cylindrical refractive power. Within the highly myopic group, as defined by an axial length that exceeded 26.5 mm, none of these associations (except for the association between axial length and spherical refractive power) were statistically significant (P > 0.15) in univariate or multivariate analysis.Conclusions: In a rural population of central India, the mean ocular axial length was 22.6 +/- 0.91 mm, which was shorter than that of other populations. Axial length was associated with the systemic parameters of increased age, taller body height, greater body mass index, and a higher level of education, and with the ocular parameters of lower best-corrected visual acuity, lower corneal refractive power, deeper anterior chamber, thicker lens, and more myopic spherical and cylindrical refractive power. These associations were valid only for those eyes that were not highly myopic, whereas axial length was associated with refractive error only in highly myopic eyes.Financial Disclosure(s): Proprietary or commercial disclosure may be found after the references. Ophthalmology 2010; 117: 1360-1366 (C) 2010 by the American Academy of Ophthalmology.