Skin deep: enhanced sleep depth by cutaneous temperature manipulation
Skin deep: enhanced sleep depth by cutaneous temperature manipulation
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DOI：
10.1093/brain/awm315
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发表时间：
2008-02-01
期刊：
影响因子：
14.5
通讯作者：
Van Someren, Eus J. W.
中科院分区：
文献类型：
--
作者：
Raymann, Roy J. E. M.;Swaaband, Dick F.;Van Someren, Eus J. W.
随着年龄的增长，越来越多的睡眠被报道为影响许多人健康和福祉的重要投诉。现有的睡眠障碍治疗方法有其局限性，因此我们采用了不同的方法来改善睡眠。由于在动物和人类研究中发现，皮肤变暖会增加与睡眠调节密切相关的大脑区域的神经元活动，因此我们研究了微妙的皮肤温度操纵是否可以改善人类睡眠。通过在夜间睡眠中使用保暖衣来控制皮肤温度，我们证明，在不改变核心温度的情况下，皮肤温度仅升高0.4摄氏度，就可以抑制夜间觉醒（P
With ageing, an increasingly disturbed sleep is reported as a significant complaint affecting the health and well-being of many people. The available treatments for sleep disturbance have their limitations, so we have adopted a different approach to the improvement of sleep. Since in animal and human studies skin warming has been found to increase neuronal activity in brain areas that are critically involved in sleep regulation, we investigated whether subtle skin temperature manipulations could improve human sleep. By employing a thermosuit to control skin temperature during nocturnal sleep, we demonstrate that induction of a mere 0.4 degrees C increase in skin temperature, whilst not altering core temperature, suppresses nocturnal wakefulness ( P