Antimicrobial resistance in human populations: challenges and opportunities.
Antimicrobial resistance in human populations: challenges and opportunities.
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DOI：
10.1017/gheg.2017.4
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发表时间：
2017
期刊：
影响因子：
--
通讯作者：
Török ME
中科院分区：
文献类型：
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作者：
Allcock S;Young EH;Holmes M;Gurdasani D;Dougan G;Sandhu MS;Solomon L;Török ME
抗菌素耐药性（AMR）是一个全球性的公共卫生威胁。抗菌素耐药性的出现是自然发生的，但也可以通过临床和兽药中的抗微生物药物暴露来选择。尽管全世界对抗菌素耐药性的关注日益增加，但我们对抗菌素耐药性在人口水平上的负担、分布和决定因素的理解仍有很大的局限性。我们强调以人群为基础的方法评估人类和动物抗菌素使用与AMR之间关系的重要性。需要这些方法来提高我们对抗菌素耐药性的发展和传播的理解，以便为抗菌素耐药性的预防、检测和管理战略提供信息，并支持在医疗保健中可持续使用抗菌素。
Antimicrobial resistance (AMR) is a global public health threat. Emergence of AMR occurs naturally, but can also be selected for by antimicrobial exposure in clinical and veterinary medicine. Despite growing worldwide attention to AMR, there are substantial limitations in our understanding of the burden, distribution and determinants of AMR at the population level. We highlight the importance of population-based approaches to assess the association between antimicrobial use and AMR in humans and animals. Such approaches are needed to improve our understanding of the development and spread of AMR in order to inform strategies for the prevention, detection and management of AMR, and to support the sustainable use of antimicrobials in healthcare.