The prevalence and associated factors for prehypertension and hypertension in Cambodia
The prevalence and associated factors for prehypertension and hypertension in Cambodia
复制标题
DOI：
10.1136/heartasia-2013-010394
复制
发表时间：
2013-01-01
期刊：
影响因子：
--
通讯作者：
Fitzpatrick, Annette L.
中科院分区：
文献类型：
--
作者：
Gupta, Vinay;LoGerfo, James P.;Fitzpatrick, Annette L.
背景高血压与不良心血管结局密切相关，是2010年全球疾病负担的主要可改变相关因素。分析可改变的相关因素对那些关心减轻高血压不良反应的人来说是很重要的。我们研究了柬埔寨25-64岁成年人高血压的相关因素，以帮助制定预防和控制高血压的新计划策略。方法使用2010年柬埔寨全国范围内评估非传染性疾病相关因素患病率的调查数据（WHO STEPs调查），5017名年龄在25岁至64岁之间的参与者被纳入高血压患病率和预测因子的二次分析中。结果高血压前期的患病率在该样本中约为总高血压的两倍（27.9%比15.3%）。男性、年龄增加和已知的心血管相关因素，包括较高的体重指数（BMI）、血脂异常、空腹血糖受损和腹部肥胖，都与高血压患病率增加相关。在多变量模型中，年龄增长是高血压最强的相关因素（OR 8.79，95%CI（5.43 ~ 14.2）），而高BMI是高血压前期的主要相关因素结论在柬埔寨，可调整的心血管相关因素与高血压前期和高血压密切相关，并且可能是公共卫生和初级保健策略的焦点，以减轻随后的缺血性心脏病和中风。一项旨在增加筛查和坚持药物治疗的国家战略是减少疾病和相关发病率负担的必要的第一步。
Background Hypertension is strongly associated with adverse cardiovascular outcomes and was the leading modifiable associated factor for global disease burden in 2010. Analysis of modifiable associated factors will be important to those concerned with mitigating the adverse effects of hypertension. We studied factors associated with hypertension in adults aged 25-64 years of age in Cambodia in order to help develop strategies for planned new initiatives for prevention and control of hypertension.Methods Using data from a nationwide survey in Cambodia assessing the prevalence of associated factors for non-communicable disease in 2010 (WHO STEPs survey), 5017 participants between the ages of 25 and 64 years were included in a secondary analysis of the prevalence and predictors of hypertension.Results The prevalence of prehypertension in this sample was approximately double that of overall hypertension (27.9% vs 15.3%). Male sex, increasing age and known cardiovascular associated factors, including higher Body Mass Index (BMI), dyslipidaemia, impaired fasting glycaemia, and abdominal obesity were all associated with an increased prevalence of hypertension. In multivariate models, increasing age was the strongest associated factor for hypertension (OR 8.79, 95% CI (5.43 to 14.2)), whereas, higher BMI was the primary associated factor associated with prehypertension (OR 3.27, 95% CI 2.21 to 4.82).Conclusions Modifiable cardiovascular-associated factors are strongly correlated with prehypertension and hypertension in Cambodia, and may be a focus of public health and primary care strategies to mitigate subsequent ischaemic heart disease and stroke. A national strategy aimed at increased screening and adherence to medical therapy is a necessary first step to reduce burden of disease and related morbidities.