BENZODIAZEPINE USE BY CHRONIC PAIN PATIENTS
BENZODIAZEPINE USE BY CHRONIC PAIN PATIENTS
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DOI：
10.1097/00002508-199006000-00013
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发表时间：
1990-01-01
影响因子：
2.9
通讯作者：
STRAIN, JJ
中科院分区：
文献类型：
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作者：
KING, SA;STRAIN, JJ
在西奈山医学院疼痛管理服务的114名慢性疼痛患者中，38%（N= 43）在初始评估时服用一种或多种苯二氮卓类药物。大多数患者是长期使用者。其中14%（N= 6）已服用药物1-2年，46%（IN= 20）已服用2年或更长时间。93%（N= 40）接受苯二氮卓类药物治疗的患者表示，疼痛发作后开始使用。尽管86%（N= 37）的患者使用药物（全部或部分）来改善睡眠，但他们继续报告与非苯二氮卓类药物组一样多的睡眠问题。与苯二氮卓类药物同时处方的其他药物为麻醉药物（58%的患者）。抗抑郁药占132%，非甾体类抗抑郁药占260%。其他（16%）：I.据报道，苯二氮卓类药物对慢性疼痛患者几乎没有治疗益处。甚至会加重他们的症状我们已经证明，苯二氮卓类药物经常被用于长期使用，用于睡眠，并与麻醉药物一起使用。这种使用违反了普遍接受的准则。
Of 114 patients presenting to the Pain Management Service at the Mount Sinai School of Medicine with chronic pain, 38%(N= 43) were taking one or more henzodiazepine drugs at the time of the initial assessment. The majority of patients were chronic users. with 14%(N= 6) having taken the medications for 1–2 years and 46%(IN= 20) for 2 years or longer. Ninety-three percent (N= 40) of those given a benzodiazepine drug stated that it was initiated after the onset of pain. Although 86%(N= 37) were using the medication (all or in part) to improve sleep, they continued to report as many problems with sleep as the nonbenzodiazepine group did. Other drugs prescribed concurrently with the benzodiazepine drugs were narcotic drugs (58%-of patients). antidepressant drugs (132%, nonsteroidal antiinflammatory agents (260). and others (16%,: I. Benzodiazepines have been reported to provide little therapeutic benefit to chronic pain patients. and may even exacerbate their symptoms. We have shown that benzodiazepine drugs are frequently prescribed for long-term use, for sleep, and in conjunction with narcotic drugs. Such use is contrary to generally accepted guidelines.