Side-related differences in sudden sensorineural hearing loss in children
Side-related differences in sudden sensorineural hearing loss in children
复制标题
儿童突发感音神经性听力损失的侧面相关差异
DOI：
10.1016/j.ijporl.2018.08.022
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发表时间：
2018-11-01
影响因子：
1.5
通讯作者：
Wu, Xuan
中科院分区：
文献类型：
--
作者：
Chen, Kaitian;Jiang, Hongyan;Wu, Xuan
目的：大多数关于儿童突发性感音神经性听力损失（SSNHL）的研究没有区分不同患耳的结果。方法：回顾性分析2003年1月至2016年12月收治的101例儿童SSNHL患者的临床资料。结果：双侧组（n = 28）与单侧组（n = 73）比较，SSNHL的性别和发病时间均无显著性差异（p > 0.05）;然而，双侧SSNHL倾向于发生在较年轻的年龄（8.1 +/- 4.0岁），可疑病因的百分比（50%）和深度耳聋的比例（55.4%，p < 0.05）更高。单侧组近期治愈率为37.0%，优于双侧组的12.5%（上级，P < 0.05）。在该队列中，较轻的初始听阈、单侧受累的早期治疗（5.6 ± 4.8天）和双侧受累病例的年龄较大（11.3 ± 3.0岁）与预后较好相关。此外，单侧组表现出可比的结果，当亚分析比较，无论是在左侧（n = 42）或右侧（n = 31）SSNHL.Conclusion：虽然双边和单边儿童SSNHL可能会导致部分到完全耳蜗病变，他们可能是相关的不同的背景。我们的数据还提供了有关儿童SSNHL的人口统计学和结果的有价值的信息。
Objective: Most studies on sudden sensorineural hearing loss (SSNHL) do not differentiate the outcomes within varied affected ears in children. The present study was designed to determine the clinical differences between unilateral and bilateral SSNHL in children.Methods: The clinical data, from a total of 101 pediatric patients with SSNHL, was retrospectively analyzed from January 2003 to December 2016. The main outcome measures included basic characteristics, etiology, clinical symptoms and treatment courses.Results: When the bilateral group (n = 28) was compared to the unilateral group (n = 73), neither gender nor onset of SSNHL was significantly different (p > 0.05 each); However, bilateral SSNHL tended to occur in younger ages (8.1 +/- 4.0 yrs), with higher percentages of suspected etiologies (50%) and proportion of profound deafness (55.4%, p < 0.05 each). The short-term recovery rate was superior in the unilateral cases over the bilateral cases (37.0% vs. 12.5%, p < 0.05). Milder initial hearing threshold, early onset of treatment (5.6 +/- 4.8 days) with unilateral involvement and an older age (11.3 +/- 3.0 yrs) in bilaterally affected cases were associated with a better prognosis in this cohort. In addition, the unilateral group showed comparable outcomes, when sub-analyzed by comparison to that in either left- (n = 42) or right-sided (n = 31) SSNHL.Conclusion: Although bilateral and unilateral pediatric SSNHL could cause partial to complete cochlear lesion, they may be relevant to distinct backgrounds. Our data also provides valuable information about demographics and outcomes of SSNHL in children.