International classification of childhood cancer, third edition
International classification of childhood cancer, third edition
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DOI：
10.1002/cncr.20910
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发表时间：
2005-04-01
期刊：
影响因子：
6.2
通讯作者：
Kaatsch, P
中科院分区：
文献类型：
--
作者：
Steliarova-Foucher, E;Stiller, C;Kaatsch, P
背景2000年出版的《国际肿瘤疾病分类》第三版（ICD-O-3）对肿瘤的编码和分类作了重大修改，特别是白血病和淋巴瘤，这是发生在儿童时期的重要癌症类别。这需要第三次修订1996年国际儿童癌症分类（ICCC-3）。ICCC-3的肿瘤分类旨在尊重几个原则：与现行国际标准一致，整合新开发的诊断技术定义的实体，与以前儿童分类的连续性，以及详尽性。ICCC-3将根据ICD-0 -3编码的肿瘤分为12个主要组，再分为47个亚组。ICCC-3的这两个级别允许与先前分类连续的儿童肿瘤大类别的标准化比较。16个最异质的亚组被进一步细分为2-11个部门，以允许在细胞遗传学或分子水平上表征的重要实体或同质肿瘤集合的研究。某些分类可能在更高级别的分类中合并，如白血病和淋巴瘤中的B细胞肿瘤。ICCC-3尊重现有的国际标准，旨在用于国际、基于人群的流行病学研究和癌症登记。国际分类系统的使用在儿科肿瘤学领域尤为重要，因为该领域的病例发生频率较低，需要严格的程序来确保数据的可比性。(c)2005年美国癌症协会。
BACKGROUND. The third edition of the International Classification of Diseases for Oncology (ICD-O-3), which was published in 2000, introduced major changes in coding and classification of neoplasms, notably for leukemias and lymphomas, which are important groups of cancer types that occur in childhood. This necessitated a third revision of the 1996 international Classification of Childhood Cancer (ICCC-3).METHODS. The tumor categories for the ICCC-3 were designed to respect several principles: agreement with current international standards, integration of the entities defined by newly developed diagnostic techniques, continuity with previous childhood classifications, and exhaustiveness.RESULTS. The ICCC-3 classifies tumors coded according to the ICD-O-3 into 12 main groups, which are split further into 47 subgroups. These 2 levels of the ICCC-3 allow standardized comparisons of the broad categories of childhood neoplasms in continuity with the previous classifications. The 16 most heterogeneous subgroups are broken down further into 2-11 divisions to allow study of important entities or homogeneous collections of tumors characterized at the cytogenetic or molecular level. Some divisions may be combined across the higher-level categories, Such as the B-cell neoplasms within leukemias and lymphomas.CONCLUSIONS. The ICCC-3 respects currently existing international standards and was designed for use in international, population-based, epidemiological studies and cancer registries. The use of an international classification system is especially important in the field of pediatric oncology, in which the low frequency of cases requires rigorous procedures to ensure data comparability. (c) 2005 American Cancer Society.