"I got a bunch of weed to help me through the withdrawals": Naturalistic cannabis use reported in online opioid and opioid recovery community discussion forums.
"I got a bunch of weed to help me through the withdrawals": Naturalistic cannabis use reported in online opioid and opioid recovery community discussion forums.
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DOI：
10.1371/journal.pone.0263583
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发表时间：
2022
期刊：
影响因子：
3.7
通讯作者：
Thrul J
中科院分区：
文献类型：
--
作者：
Meacham MC;Nobles AL;Tompkins DA;Thrul J
越来越多的研究报告了大麻和大麻素的潜在阿片类药物节约作用，但对具体机制知之甚少。本研究审查了Reddit平台上两个大型在线社区(“subreddits”)中与大麻有关的帖子，以比较自认为积极使用阿片类药物的人与正在康复的人提到的自然大麻使用情况。我们从2015年12月到2019年8月从一个阿片类药物使用subreddit和一个阿片类药物恢复subreddit中提取了所有提到大麻相关关键词(例如，“大麻”、“大麻”、“大麻”)的帖子。为了调查大麻是如何在规模上被讨论的，我们使用词频倒置文档频率(TF-IDF)权重确定并比较了每个子编辑网站中与大麻相关的帖子中最频繁的短语。为了将这些发现与背景联系起来，我们还对200篇随机发布的帖子(每个子编辑网站100篇)进行了定性的内容分析。与大麻有关的职位在戒毒所(n=908；16,791个职位中占5.4%)中的普及率约为积极使用阿片类药物(n=4,224；159,994个职位中的2.6%，p<；.001)的两倍。Recovery Subreddit中最频繁的短语提到了没有使用阿片类药物的时间，以及使用大麻作为“治疗”的可能性。阿片类药物编辑小组中最频繁的短语提到同时使用大麻和阿片类药物。使用大麻的最常见动机是为了控制康复亚危险药物中的阿片类药物戒断症状，通常与抗焦虑和胃肠道痛苦的“安慰剂”一起使用，并在阿片类药物亚危险药物中与阿片类药物联合使用时增强“快感”。尽管化名在线帖子在概括性方面存在限制，但对自然大麻使用与阿片类药物使用有关的报告的审查发现，戒断症状管理是一个共同的动机。今后的研究需要更有条理的评估，审查大麻和大麻素在解决阿片类药物戒断的躯体和情感症状方面的作用。
A growing body of research has reported on the potential opioid-sparing effects of cannabis and cannabinoids, but less is known about specific mechanisms. The present research examines cannabis-related posts in two large online communities on the Reddit platform (“subreddits”) to compare mentions of naturalistic cannabis use by persons self-identifying as actively using opioids versus persons in recovery. We extracted all posts mentioning cannabis-related keywords (e.g., “weed”, “cannabis”, “marijuana”) from December 2015 through August 2019 from an opioid use subreddit and an opioid recovery subreddit. To investigate how cannabis is discussed at-scale, we identified and compared the most frequent phrases in cannabis-related posts in each subreddit using term-frequency-inverse document frequency (TF-IDF) weighting. To contextualize these findings, we also conducted a qualitative content analysis of 200 random posts (100 from each subreddit). Cannabis-related posts were about twice as prevalent in the recovery subreddit (n = 908; 5.4% of 16,791 posts) than in the active opioid use subreddit (n = 4,224; 2.6% of 159,994 posts, p < .001). The most frequent phrases from the recovery subreddit referred to time without using opioids and the possibility of using cannabis as a “treatment.” The most frequent phrases from the opioid subreddit referred to concurrent use of cannabis and opioids. The most common motivations for using cannabis were to manage opioid withdrawal symptoms in the recovery subreddit, often in conjunction with anti-anxiety and GI-distress “comfort meds,” and to enhance the “high” when used in combination with opioids in the opioid subreddit. Despite limitations in generalizability from pseudonymous online posts, this examination of reports of naturalistic cannabis use in relation to opioid use identified withdrawal symptom management as a common motivation. Future research is warranted with more structured assessments that examines the role of cannabis and cannabinoids in addressing both somatic and affective symptoms of opioid withdrawal.
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影响因子：
3.7
作者：
Franklyn AM;Eibl JK;Gauthier GJ;Marsh DC
通讯作者：
Marsh DC
影响因子：
4.4
作者：
Enghoff, Oskar;Aldridge, Judith
通讯作者：
Aldridge, Judith
影响因子：
39
作者：
Bachhuber, Marcus A.;Saloner, Brendan;Cunningham, Chinazo O.;Barry, Colleen L.
通讯作者：
Barry, Colleen L.
DOI：
10.1007/s11414-018-9616-9
发表时间：
2019-04-01
影响因子：
1.9
作者：
Croff, Raina;Hoffman, Kim;Schmidt, Laura
通讯作者：
Schmidt, Laura
DOI：
10.1002/asi.23880
发表时间：
2017-10-01
影响因子：
3.5
作者：
Costello, Kaitlin L.;Martin, John D., III;Brinegar, Ashlee Edwards
通讯作者：
Brinegar, Ashlee Edwards