Advanced scanning methods with tracking optical coherence tomography
Advanced scanning methods with tracking optical coherence tomography
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DOI：
10.1364/opex.13.007937
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发表时间：
2005-10-03
期刊：
影响因子：
3.8
通讯作者：
Schuman, JS
中科院分区：
文献类型：
--
作者：
Hammer, DX;Ferguson, RD;Schuman, JS
介绍了一种升级的集成视网膜跟踪器(TOCT)的光学相干层析成像系统。升级后的系统使用改进的组件来扩展跟踪带宽，将跟踪硬件完全集成到临床OCT系统的光学头中，并在单一软件平台上运行。该系统能够实现亚像素精度(类似于10微米)的横向扫描配准。我们用TOCT演示了几种先进的扫描序列，包括连续和几个小时间隔的多次B超的平均(联合添加)扫描，通过汇总圆形、线状和栅格扫描的A扫描收集的面部图像，以及中心凹和视盘的三维(3D)视网膜图。与单次扫描相比，新系统实现了高精度的OCT扫描配准，生成的复合图像的空间分辨率显著提高，信噪比增加，斑点减少，同时保持了清晰的边界和清晰的精细结构。在单独的成像过程中精确地重新配准多个扫描，证明了TOCT在纵向研究中的有效性。从这些数据生成的人脸图像和3D数据立方体显示了高保真图像与跟踪，尽管扫描持续时间超过一分钟。(C)2005年美国光学学会。
An upgraded optical coherence tomography system with integrated retinal tracker (TOCT) was developed. The upgraded system uses improved components to extend the tracking bandwidth, fully integrates the tracking hardware into the optical head of the clinical OCT system, and operates from a single software platform. The system was able to achieve transverse scan registration with sub-pixel accuracy (similar to 10 mu m). We demonstrate several advanced scan sequences with the TOCT, including composite scans averaged (co-added) from multiple B-scans taken consecutively and several hours apart, en face images collected by summing the A-scans of circular, line, and raster scans, and three-dimensional (3D) retinal maps of the fovea and optic disc. The new system achieves highly accurate OCT scan registration yielding composite images with significantly improved spatial resolution, increased signal-to-noise ratio, and reduced speckle while maintaining well-defined boundaries and sharp fine structure compared to single scans. Precise re-registration of multiple scans over separate imaging sessions demonstrates TOCT utility for longitudinal studies. En face images and 3D data cubes generated from these data reveal high fidelity image registration with tracking, despite scan durations of more than one minute. (c) 2005 Optical Society of America.