A Two-Dimensional Metal-Organic Framework as a Fluorescent Probe for Ascorbic Acid Sensing
A Two-Dimensional Metal-Organic Framework as a Fluorescent Probe for Ascorbic Acid Sensing
复制标题
二维金属有机框架作为抗坏血酸传感荧光探针
DOI：
10.1002/ejic.201701079
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发表时间：
2018
影响因子：
2.3
通讯作者：
Qian Guodong
中科院分区：
文献类型：
--
作者：
Yue Dan;Huang Yike;Zhang Jun;Zhang Xin;Cui Yuanjing;Yang Yu;Qian Guodong
抗坏血酸（AA）是一种重要的生物分子，但AA的检测仍然是一个巨大的挑战。因此，迫切需要高灵敏度和高选择性的AA荧光传感器。本论文以4，4 ′-（1H-吡唑-1，3-二基）二苯甲酸（H2 L）为有机连接剂，构建了新型二维金属有机骨架（MOF）ZnL（H2O）（ZJU-137，ZJU =浙江大学）。ZJU-137 MOF通过荧光猝灭对AA的检测表现出高选择性和灵敏度。AA的检测限为34 nM，并且观察到宽的线性浓度依赖性响应（0-60 µm）;因此，ZJU-137在实际应用中具有很好的AA测定潜力。
Ascorbic acid (AA) is an important biological molecule, but the detection of AA is still a huge challenge. Therefore, highly sensitive and selective fluorescent sensors for AA determination are urgently demanded. In this work, the new organic linker 4,4′‐(1H‐pyrazole‐1,3‐diyl)dibenzoic acid (H2L) was prepared to construct the new two‐dimensional metal–organic framework (MOF) ZnL(H2O) (ZJU‐137, ZJU = Zhejiang University). The ZJU‐137 MOF demonstrates high selectivity and sensitivity for the detection of AA through fluorescence quenching. The detection limit for AA was 34 nM, and a wide linear concentration‐dependent response (0–60 µm) was observed; hence, ZJU‐137 has promising potential for the determination of AA in practical applications.