POPCORN CALCIFICATIONS - A PROGNOSTIC SIGN IN OSTEOGENESIS IMPERFECTA
POPCORN CALCIFICATIONS - A PROGNOSTIC SIGN IN OSTEOGENESIS IMPERFECTA
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DOI：
10.1148/radiology.136.2.7403509
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发表时间：
1980-01-01
期刊：
影响因子：
19.7
通讯作者：
BULLOUGH, PG
中科院分区：
文献类型：
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作者：
GOLDMAN, AB;DAVIDSON, D;BULLOUGH, PG
爆米花样钙化在X线摄影上表现为扇形透亮线的集合，每个透亮线边缘都有阴影，在某些情况下，中央有密度。回顾性分析了46例儿童成骨不全的X线片; 52%的儿童在1个或多个部位有爆米花状钙化。这些病变仅在活跃的骨骼生长期间观察到，在出生时不存在，主要发生在膝盖和脚踝周围，并且与正常水平生长板的不规则或缺失相关。根据多个X线观察，爆米花状钙化似乎是骨骺板碎裂和无序成熟的结果。它们的存在表明内软骨骨化障碍，这可能导致与骨生成相关的严重生长迟缓。
Popcorn calcifications appear roentgenographically as a collection of scalloped radiolucencies, each with a sclerotic margin and, in some instances, with central densities. Radiographs of 46 children with osteogenesis imperfecta were reviewed retrospectively; 52% had popcorn calcifications at 1 or more sites. These lesions are observed only during active skeletal growth, are not present at birth, occur predominantly around the knees and ankles and are associated with irregularity or absence of the normal horizontal growth plate. Based on multiple roentgen observations, popcorn calcifications appear to result from fragmentation and disordered maturation of the physis. Their presence indicates a disturbance in enchondral ossification which may contribute to the severe growth retardation associated with osteogenesis imperfecta.