Blistering disorders: diagnosis and treatment.
Blistering disorders: diagnosis and treatment.
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DOI：
10.1046/j.1529-8019.2003.01631.x
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发表时间：
2003-01-01
影响因子：
3.6
通讯作者：
Razzaque Ahmed, A
中科院分区：
文献类型：
--
作者：
Yeh, S W;Ahmed, Babar;Razzaque Ahmed, A
水疱性疾病是一组异质性疾病，可影响皮肤和粘膜，或两者，在表现、临床过程、病理组织学、免疫病理学和治疗方面各不相同。诊断延误的情况并不少见。这可能导致严重的，有时甚至是致命的后果。虽然这些疾病是罕见的，但根据临床特征和实验室观察相结合做出准确的诊断是非常重要的。简要回顾了以下大疱性疾病：天疱疮，副肿瘤性天疱疮，大疱性类天疱疮，瘢痕性类天疱疮，获得性大疱性表皮炎，疱疹样皮炎，线性伊加大疱性疾病，迟发性皮肤卟啉病，和角膜下脓疱性皮炎。他们的临床，病理组织学和免疫病理学特征和治疗建议进行了讨论。
Blistering diseases are a heterogeneous group of disorders that can affect either skin and mucous membrane, or both, varying in presentation, clinical course, pathohistology, immunopathology and treatment. Not infrequently the diagnosis is delayed. This can result in severe, and sometimes fatal consequences. Although these diseases are rare, it is very important to make an accurate diagnosis based on a combination of clinical profile and laboratory observations. A brief review is presented of the following bullous diseases: pemphigus, paraneoplastic pemphigus, bullous pemphigoid, cicatricial pemphigoid, epidermolysis bullosa acquisita, dermatitis herpetiformis, linear IgA bullous disease, porphyria cutanea tarda, and subcorneal pustular dermatitis. Their clinical, pathohistologic and immunopathologic features and recommendations for therapy are discussed.