Development of low laser energy levels in small-incision lenticule extraction: clinical results, black area, and ultrastructural evaluation
Development of low laser energy levels in small-incision lenticule extraction: clinical results, black area, and ultrastructural evaluation
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小切口微透镜提取中低激光能量水平的发展：临床结果、黑色区域和超微结构评估
DOI：
10.1097/j.jcrs.0000000000000071
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发表时间：
2020-03-01
影响因子：
2.8
通讯作者：
Liu, Quan
中科院分区：
文献类型：
--
作者：
Lin, Limian;Weng, Shengbei;Liu, Quan
目的：评价小切口摘出术（SMILE）后4种低激光能量水平的结局。设置：中国广州中山眼科中心。设计：前瞻性随机临床试验。方法：本研究评价了连续患者接受SMILE矫正近视或近视伴散光。根据手术期间使用的激光能量（即105 nJ、110 nJ、115 nJ或120 nJ）将眼睛分组。所有患者在术前和术后3个月内的4个时间点进行了全面的眼科检查。结果：62例患者（女40例，男22例）124眼，每组31眼，术后随访1~12个月。在105 nJ、110 nJ、115 nJ和120 nJ时，黑色区域的发生率分别为45.16%（14/31眼）、12.90%（4/31眼）、16.13%（5/31眼）和12.90%（4/31眼）。在105 nJ组中，创建小球的平均时间最长（P = 0.015）。术后角膜厚度增加最多的是105 nJ（P
Purpose: To evaluate the outcomes of 4 low laser energy levels after small-incision lenticule extraction (SMILE) surgery.Setting: Zhongshan Ophthalmic Center, Guangzhou, China.Design: Prospective randomized clinical trial.Methods: This study evaluated consecutive patients who had SMILE to correct myopia or myopia with astigmatism. Eyes were placed into groups based on the laser energy used during surgery (ie, 105 nJ, 110 nJ, 115 nJ, or 120 nJ). All patients had a thorough ophthalmic examination preoperative and at 4 timepoints over 3 months postoperatively. Black areas and surface regularity of the extracted lenticules were observed and evaluated qualitatively and quantitatively.Results: The study comprised 124 eyes of 62 patients (40 women, 22 men), with 31 eyes in each laser energy group. The incidence of black areas was 45.16% (14 of 31 eyes), 12.90% (4 of 31 eyes), 16.13% (5 of 31 eyes), and 12.90% (4 of 31 eyes) for 105 nJ, 110 nJ, 115 nJ, and 120 nJ, respectively. The mean time for lenticule creation was the longest in the 105 nJ group (P =.015). The greatest increase in corneal thickness postoperatively occurred with 105 nJ (P