Quality of life in cancer survivorship: Sociodemographic and disease-related moderators
Quality of life in cancer survivorship: Sociodemographic and disease-related moderators
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DOI：
10.1111/ecc.13692
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发表时间：
2022-09-07
影响因子：
2.1
通讯作者：
Arribas, Leoncio
中科院分区：
文献类型：
--
作者：
Andreu, Yolanda;Martinez, Paula;Arribas, Leoncio
发现高危幸存者以便提供适当的护理。目的分析癌症幸存者的生活质量（QOL），使用专门为该人群设计的工具，并考虑不同的社会人口统计学和疾病相关特征作为可能的调节变量。方法对1862例西班牙无病癌症治疗后幸存者进行生活质量调查（QLACS）。结果：QLACS评分与其他研究中获得的结果相当，并且作为初级治疗结束后较短时间的函数，表明较差的生活质量。前列腺癌患者的生活质量最好，血液病患者的生活质量最差。全身治疗（化疗加激素治疗）和放化疗联合治疗均与较差的生活质量相关。同样，年龄较小、女性、失业状况和没有稳定的伴侣也与较差的生活质量有关。结论进一步了解已经庞大且持续增长的癌症幸存者群体的生活质量，对指导临床实践和卫生政策具有重要意义。此外，了解与生活质量恶化相关的风险因素有助于为最需要的幸存者制定有针对性的预防规划。
Rationale To identify high-risk survivors in order to provide appropriate care. Purpose To analyse the quality of life (QOL) of cancer survivors using an instrument designed specifically for this population and considering different sociodemographic and disease-related characteristics as possible modulating variables. Methods The Quality of Life in Adult Cancer Survivors (QLACS) was filled out by a large and heterogeneous sample of disease-free post-treatment Spanish cancer survivors (N = 1862). Results QLACS scores were comparable to those obtained in other studies and indicative of worse QOL as a function of shorter elapsed time since the end of primary treatment. The best QOL was shown by prostate, and the worst by hematologic cancer survivors. Both systemic treatments (chemotherapy and hormone therapy) and the combination of radiotherapy and chemotherapy were associated with worse QOL. Likewise, younger age, female sex, unemployment status and not having a stable partner were associated with worse QOL. Conclusion Greater understanding of the QOL experienced by the already large and continuously growing population of cancer survivors is relevant for guiding both clinical practice and health policy. In addition, knowing the risk factors associated with worse QOL facilitates the development of targeted prevention programmes for those survivors who need it the most.