Plasmid pAMS1-Encoded, Bacteriocin-Related “Siblicide” in Enterococcus faecalis
Plasmid pAMS1-Encoded, Bacteriocin-Related “Siblicide” in Enterococcus faecalis
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DOI：
10.1128/jb.00147-09
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发表时间：
2009-03
影响因子：
3.2
通讯作者：
C. Sedgley;D. Clewell;S. Flannagan
中科院分区：
文献类型：
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作者：
C. Sedgley;D. Clewell;S. Flannagan
粪肠球菌IIa类细菌素MC 4 -1由性信息素应答的多重抗生素抗性质粒pAMS 1编码，在一定条件下具有“同胞杀”活性。含有质粒的细胞在含有相同（含有质粒的）菌株的细菌菌苔的固体培养基上的刺戳产生抑制区。如果含有质粒的宿主也产生明胶酶，则不能检测到细菌素。
ABSTRACT The Enterococcus faecalis class IIa bacteriocin MC4-1 encoded by the sex pheromone-responding, multiple-antibiotic resistance plasmid pAMS1 exhibits “siblicidal” (sibling-killing) activity under certain conditions. Stabs of plasmid-containing cells on solid medium containing lawns of bacteria of the same (plasmid-containing) strain give rise to zones of inhibition. If the plasmid-containing host also produces gelatinase, bacteriocin cannot be detected.